Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11160859 | 0.78 | RAB9A (0.47) | RAB9AIDO1ALDH1A1MAPTMEN1 | |
| SCHEMBL2200685 | 0.75 | MC4R (0.48) | RAB9AIDO1ALDH1A1AKR1C3HTT | |
| SCHEMBL1013 | 0.74 | IDO1 (0.62) | RAB9AIDO1ALDH1A1AKR1C3HTT | |
| SCHEMBL11085603 | 0.73 | IDO1 (0.54) | RAB9AIDO1ALDH1A1MAPTAKR1C3 | |
| SCHEMBL15618793 | 0.73 | ALDH1A1 (0.55) | RAB9AIDO1ALDH1A1MAPTAKR1C3 | |
| SCHEMBL9878050 | 0.73 | ALDH1A1 (0.45) | RAB9AIDO1ALDH1A1MAPTMEN1 | |
| Cysteamine SCHEMBL10673341 | 0.72 | IDO1 (0.53) | RAB9AIDO1ALDH1A1AKR1C3HTT | |
| SCHEMBL9878438 | 0.72 | RAB9A (0.42) | RAB9AIDO1ALDH1A1MAPTMEN1 | |
| SCHEMBL10989032 | 0.72 | RAB9A (0.59) | RAB9AIDO1ALDH1A1MAPTMEN1 | |
| SCHEMBL27388024 | 0.71 | IDO1 (0.51) | RAB9AIDO1ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992542-A | Thienamycin antibiotics | MERCK & CO., INC. (US) | 1991-02-12 | — | — | US | disclosed |