Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089703 | 0.80 | HPGD (0.39) | MAPTTNKS2TDP1ALDH1A1LMNA | |
| SCHEMBL11657580 | 0.63 | — | — | |
| SCHEMBL10842827 | 0.60 | MAPT (0.50) | MEN1KMT2AMAPTGAARAB9A | |
| SCHEMBL6525869 | 0.59 | ACHE (0.50) | MEN1KMT2AMAPTATMNPSR1 | |
| SCHEMBL21579390 | 0.58 | MEN1 (0.41) | MEN1KMT2AMAPTGAARAB9A | |
| SCHEMBL10559578 | 0.57 | MEN1 (1.00) | MEN1KMT2AMAPTGAARAB9A | |
| SCHEMBL5702878 | 0.57 | — | — | |
| SCHEMBL15393057 | 0.57 | ACHE (0.47) | MEN1KMT2AMAPTATMNPSR1 | |
| SCHEMBL11960959 | 0.57 | CYP19A1 (0.44) | MEN1KMT2AMAPTATMNPSR1 | |
| SCHEMBL14665739 | 0.57 | MEN1 (0.54) | MEN1KMT2AMAPTGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994474-A | Hypotensive agents | SANOFI (FR) | 1991-02-19 | — | — | US | disclosed |