Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11621275 | 0.85 | KDM4E (0.40) | SCN9ANPC1HPGDRAB9AL3MBTL1 | |
| SCHEMBL11623976 | 0.84 | MGLL (0.37) | MEN1KMT2ANPC1HPGDRAB9A | |
| SCHEMBL11620754 | 0.81 | KMT2A (0.46) | SCN9AMEN1KMT2ANPC1HPGD | |
| SCHEMBL11623460 | 0.81 | ALDH1A1 (0.40) | MEN1KMT2AHPGDALDH1A1MAPT | |
| SCHEMBL11624495 | 0.80 | KMT2A (0.39) | SCN9AMEN1KMT2ACNR2NPC1 | |
| SCHEMBL11622693 | 0.77 | GPBAR1 (0.40) | MEN1KMT2ATSPODGAT2GPBAR1 | |
| SCHEMBL11624087 | 0.77 | PDE4B (0.38) | SCN9AMEN1KMT2ACNR2NPC1 | |
| SCHEMBL11622099 | 0.76 | GPBAR1 (0.39) | MEN1KMT2ANPC1HPGDRAB9A | |
| SCHEMBL11620478 | 0.75 | GPBAR1 (0.38) | MEN1KMT2ACNR2TSPODGAT2 | |
| SCHEMBL11623925 | 0.73 | SCN9A (0.41) | SCN9AMEN1KMT2AALPLTSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072498-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | claimed |
| US-4988725-A | Cardiovascular disorders, antiarrhythmia agents | STERLING DRUG INC. (US) | 1991-01-29 | — | — | US | disclosed |
| EP-0388654-A2 | Azole-1-alkanamides as antiarrhythmic agents and preparation thereof | STERLING DRUG INC. (US) | 1990-09-26 | — | — | EP | disclosed |
| US-4072498-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | disclosed |