Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6051201 | 0.78 | KDM4E (0.46) | KDM4EMAPTALDH1A1TDP1NPC1 | |
| SCHEMBL11687562 | 0.76 | L3MBTL1 (0.57) | KDM4EMAPTALDH1A1TDP1NPC1 | |
| SCHEMBL11686414 | 0.76 | KDM4E (0.56) | KDM4EMAPTALDH1A1TDP1NPC1 | |
| SCHEMBL9877301 | 0.74 | TDP1 (0.54) | KDM4EMAPTALDH1A1TDP1NPC1 | |
| SCHEMBL6051319 | 0.74 | L3MBTL1 (0.58) | KDM4EMAPTALDH1A1TDP1NPC1 | |
| SCHEMBL11796771 | 0.72 | KDM4E (0.62) | KDM4EMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL6051311 | 0.72 | KDM4E (0.57) | KDM4EMAPTALDH1A1TDP1NPC1 | |
| SCHEMBL11515706 | 0.71 | KDM4E (0.64) | KDM4EMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL8937738 | 0.70 | TYR (0.49) | KDM4EMAPTALDH1A1TDP1NPC1 | |
| SCHEMBL11759262 | 0.70 | TYR (0.49) | KDM4EMAPTALDH1A1TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001171-A | Process, modified rubbers and rubber compositions | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0319733-A2 | Process, modified rubbers and rubber compositions | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1989-06-14 | — | — | EP | disclosed |
| US-4788229-A | BLENDING MIXTURES OF UNCURED ELASTOMERS AND FILLERS CONTAINING ELASTOMER-FILLER LINKAGE PROMOTERS; TIRES; FRICTION RESISTANCE; REDUCED HYSTERESIS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1988-11-29 | — | — | US | disclosed |
| US-4624977-A | NATURAL OR SYNTHETIC RUBBER DENATURED NITROSOQUINOLINE, CARBON BLACK | BRIDGESTONE CORPORATION (JP) | 1986-11-25 | — | — | US | disclosed |