Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16632208 | 1.00 | CA4 (0.36) | CA4CA2CA5ASRCPTPN1 | |
| SCHEMBL4830594 | 0.90 | SRC (0.38) | CA4CA2CA5ASRCPTPN1 | |
| SCHEMBL9854058 | 0.83 | ALDH1A1 (0.45) | ALDH1A1 | |
| Lindane SCHEMBL10824407 | 0.83 | SRC (0.33) | CA4CA2CA5ASRCPTPN1 | |
| SCHEMBL37140 | 0.80 | — | — | |
| SCHEMBL11764317 | 0.78 | MMP1 (0.34) | CA4CA2CA5AALDH1A1CA6 | |
| Aniline SCHEMBL4894703 | 0.78 | TSHR (0.41) | CA4CA2CA5ASRCCA9 | |
| Formaldehyde SCHEMBL27942429 | 0.78 | CA4 (0.38) | CA4ALDH1A1CA6CA7CA9 | |
| SCHEMBL4830589 | 0.77 | CA4 (0.34) | CA4CA6CA7CA9CA14 | |
| Ammonia Solution, Strong SCHEMBL23611461 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023253-A | Antitumor agents | UNIVERSITY PATENTS, INC. (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0324109-A2 | 6-substituted mitomycin analogs | UNIVERSITY PATENTS, INC. (US) | 1989-07-19 | — | — | EP | disclosed |
| WO-1989005811-A1 | NEW 6-SUBSTITUTED MITOMYCIN ANALOGS | UNIVERSITY PATENTS, INC. (US) | 1989-06-29 | — | — | WO | disclosed |