Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | GBA1 | P04062 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 8/20 | 0.56 |
| ▸ | MMP13 | P45452 | 5/20 | 0.56 |
| ▸ | MMP3 | P08254 | 3/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.55 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.55 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 10/20 | 0.54 |
| ▸ | MMP7 | P09237 | 3/20 | 0.54 |
| ▸ | MMP1 | P03956 | 3/20 | 0.54 |
| ▸ | MMP10 | P09238 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 2/20 | 0.50 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24130567 | 1.00 | ALDH1A1 (0.63) | ALDH1A1TSHRTDP1GBA1MMP2 | |
| SCHEMBL8016553 | 0.85 | TDP1 (0.59) | ALDH1A1TSHRTDP1MMP2MMP13 | |
| SCHEMBL8006415 | 0.85 | MMP7 (0.70) | ALDH1A1TSHRTDP1GBA1MMP2 | |
| SCHEMBL24130608 | 0.85 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1GBA1MMP2 | |
| SCHEMBL5193396 | 0.84 | TDP1 (0.64) | ALDH1A1TDP1MMP2MMP13MMP3 | |
| SCHEMBL3427026 | 0.84 | TDP1 (0.64) | TDP1MMP2MMP13MMP3SLC1A3 | |
| SCHEMBL3397101 | 0.84 | TDP1 (0.64) | TDP1MMP2MMP13MMP3SLC1A3 | |
| SCHEMBL35211007 | 0.84 | TDP1 (0.64) | ALDH1A1TDP1MMP2MMP13MMP3 | |
| SCHEMBL3392197 | 0.84 | TDP1 (0.64) | TDP1MMP2MMP13MMP3SLC1A3 | |
| SCHEMBL1734695 | 0.84 | TDP1 (0.64) | ALDH1A1TDP1MMP2MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049667-A | Nitrogen-containing cyclic ligands | GUERBET S.A. (FR) | 1991-09-17 | — | — | US | disclosed |