Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29657671 | 0.69 | KMT2A (0.64) | MEN1KMT2ACYP1A2 | |
| SCHEMBL255964 | 0.69 | KMT2A (0.64) | MEN1KMT2ACYP1A2 | |
| SCHEMBL3237282 | 0.68 | GPR3 (0.36) | MEN1KMT2AACHECYP1A2 | |
| SCHEMBL25757622 | 0.65 | MEN1 (0.41) | MEN1KMT2ACYP1A2 | |
| SCHEMBL2634004 | 0.63 | TSHR (0.42) | ACHECYP1A2 | |
| SCHEMBL29404850 | 0.63 | TSHR (0.42) | ACHECYP1A2 | |
| SCHEMBL7332054 | 0.63 | — | — | |
| SCHEMBL29965099 | 0.63 | — | — | |
| SCHEMBL121521 | 0.63 | — | — | |
| SCHEMBL255961 | 0.60 | MEN1 (0.46) | MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003097-A | Method for the sulfurization of phosphorous groups in compounds | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1991-03-26 | — | — | US | claimed |
| US-12030864-B2 | Small molecule anticancer agents, combinations and uses thereof | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-07-09 | — | — | US | disclosed |
| US-20210147379-A1 | NOVEL SMALL MOLECULE ANTICANCER AGENTS, COMBINATIONS AND USES THEREOF | University of Florda Research Foundation,Incorporated (US) | 2021-05-20 | — | — | US | disclosed |
| US-20170240570-A1 | NOVEL SMALL MOLECULE ANTICANCER AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2017-08-24 | — | — | US | disclosed |
| US-20170240570-A1 | NOVEL SMALL MOLECULE ANTICANCER AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2017-08-24 | — | — | US | disclosed |
| WO-2016061555-A2 | NOVEL SMALL MOLECULE ANTICANCER AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2016-04-21 | — | — | WO | disclosed |
| US-5003097-A | Method for the sulfurization of phosphorous groups in compounds | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1991-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147379-A1 | NOVEL SMALL MOLECULE ANTICANCER AGENTS, COMBINATIONS AND USES THEREOF | MKI67, TP53, PLK1 | MEN1 2251/4885KMT2A 2007/4885ACHE 4792/4885 |
| US-12030864-B2 | Small molecule anticancer agents, combinations and uses thereof | MKI67, TP53, PCNA | MEN1 1485/4885KMT2A 1932/4885ACHE 4772/4885 |
| US-20170240570-A1 | NOVEL SMALL MOLECULE ANTICANCER AGENTS | MKI67, TP53, PCNA | MEN1 2305/4885KMT2A 2006/4885ACHE 4874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.