Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255964 | 0.77 | KMT2A (0.64) | MEN1KMT2ACYP1A2TSHRMAOA | |
| SCHEMBL29657671 | 0.77 | KMT2A (0.64) | MEN1KMT2ACYP1A2TSHRMAOA | |
| SCHEMBL11750709 | 0.67 | CES1 (0.39) | MEN1KMT2ACYP1A2TSHRCES1 | |
| SCHEMBL255961 | 0.67 | MEN1 (0.46) | MEN1KMT2ACYP1A2TSHRMAOA | |
| Hydrochloric Acid SCHEMBL11752423 | 0.65 | CES1 (0.38) | MEN1KMT2ACYP1A2TSHRMAOA | |
| SCHEMBL15379971 | 0.65 | PNMT (0.37) | MEN1KMT2ACYP1A2MAOBCA12 | |
| SCHEMBL9877879 | 0.65 | MEN1 (0.35) | MEN1KMT2ACYP1A2 | |
| SCHEMBL14094071 | 0.65 | KMT2A (0.35) | MEN1KMT2ACYP1A2MAOAMAOB | |
| SCHEMBL24038405 | 0.65 | MAOA (0.39) | MEN1KMT2ACYP1A2TSHRMAOA | |
| SCHEMBL8217215 | 0.65 | TSHR (0.38) | MEN1KMT2ACYP1A2TSHRMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098880-A1 | FUSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 | 2023-06-08 | — | — | WO | disclosed |