SCHEMBL987797

SCHEMBL987797

C#Cc1ccc(CC=C)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
CYP3A4 P08684 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
TP53 P04637 1/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
ALOX12 P18054 1/20 0.47
XDH P47989 1/20 0.42
MAPT P10636 3/20 0.41
GABRA1 P14867 3/20 0.41
GABRB2 P47870 3/20 0.41
CNR2 P34972 3/20 0.41
PPARG P37231 2/20 0.41
PPARD Q03181 2/20 0.41
MEN1 O00255 2/20 0.41
GAA P10253 2/20 0.41
CNR1 P21554 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH2 P05091 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Allylbenzene SCHEMBL9309629 0.85 MAOB (0.43) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL173301 0.80 ALDH1A1 (0.64) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL1008236 0.79 CA12 (0.40) HDAC8CA12CA1CA2CA4
SCHEMBL8812675 0.78 HDAC8 (0.35) HDAC8CA12CA1CA2CA4
SCHEMBL991288 0.77 LOXL2 (0.52) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL6919173 0.77 ALDH1A1 (0.47) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL4349882 0.77 ALDH1A1 (0.47) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
Bromide SCHEMBL8645583 0.77 ALDH1A1 (0.61) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
Phosphine SCHEMBL28908227 0.77 ALDH1A1 (0.61) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
Water SCHEMBL29179560 0.77 ALDH1A1 (0.61) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114534707-B Alkenyl benzene compound C=C isomerization catalyst and preparation method and application thereof 中国科学院理化技术研究所 2024-03-01 CN claimed
JP-1305040-A None JP disclosed
JP-7101888-A None JP disclosed
JP-4021640-A None JP disclosed
JP-62298545-A None JP disclosed
JP-61197543-A None JP disclosed
JP-6321844-A None JP disclosed
JP-61140535-A None JP disclosed
JP-61140579-A None JP disclosed
CN-114713231-B Alkenyl benzene compound isomerization catalyst and preparation method and application thereof 中国科学院理化技术研究所 2024-05-07 CN disclosed
EP-0249933-B1 NOVEL OPTICALLY ACTIVE TOLAN DERIVATIVES AND PROCESS FOR PREPARING SAME DAINIPPON INK AND CHEMICALS, INC. (JP) 1990-05-23 EP disclosed
JP-H01305040-A 1-(4-ALKYLPHENYLETHYNYL)-4-)ALKYLPHENYLETHYNYL)-BENZENE CHISSO CORP 1989-12-08 JP disclosed
US-4814516-A LIQUID CRYSTALS DAINIPPON INK & CHEMICALS, INC. (JP) 1989-03-21 US disclosed
US-4754051-A LIQUID CRYSTALS; DISPLAYS DAINIPPON INK AND CHEMICALS, INC. (JP) 1988-06-28 US disclosed
JP-S62298545-A NOVEL OPTICALLY ACTIVE TOLAN COMPOUND DAINIPPON INK & CHEM INC 1987-12-25 JP disclosed
EP-0249933-A1 Novel optically active tolan derivatives and process for preparing same DAINIPPON INK AND CHEMICALS, INC. (JP) 1987-12-23 EP disclosed
EP-0217354-A1 Novel optically active tolan derivative DAINIPPON INK AND CHEMICALS, INC. (JP) 1987-04-08 EP disclosed
JP-S61197543-A NOVEL TOLAN ESTER DAINIPPON INK & CHEM INC 1986-09-01 JP disclosed
JP-S61140579-A NOVEL TOLAN-TYPE NEMATIC LIQUID CRYSTAL COMPOUND DAINIPPON INK & CHEM INC 1986-06-27 JP disclosed
JP-S61140535-A NOVEL TOLAN-TYPE NEMATIC LIQUID CRYSTAL COMPOUND DAINIPPON INK & CHEM INC 1986-06-27 JP disclosed