Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.46 |
| ▸ | CD38 | P28907 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13028401 | 0.88 | ESR1 (0.38) | MEN1HPGDTSHRKMT2ACES2 | |
| SCHEMBL9807751 | 0.86 | CYP19A1 (0.46) | CYP19A1TDP1 | |
| SCHEMBL13028410 | 0.84 | CYP3A4 (0.41) | MEN1HPGDKMT2ACYP19A1TDP1 | |
| SCHEMBL30580646 | 0.81 | LTA4H (0.47) | KMT2ACES2CES1SLC6A7CYP19A1 | |
| SCHEMBL13028408 | 0.81 | ADH5 (0.51) | TSHRSLC6A7CYP19A1 | |
| SCHEMBL31388182 | 0.80 | CYP19A1 (0.52) | MEN1KMT2ACYP19A1EPHX2 | |
| SCHEMBL18280916 | 0.80 | ADH5 (0.54) | MEN1TSHRKMT2ACYP19A1 | |
| SCHEMBL9879507 | 0.78 | LSS (0.47) | KMT2ACES2CES1SLC6A7CYP19A1 | |
| SCHEMBL4808545 | 0.78 | CYP19A1 (0.48) | HPGDCES2CES1CYP19A1GAA | |
| SCHEMBL11106769 | 0.78 | MAOB (0.46) | KMT2ACES2CES1SLC6A7CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991012255-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-22 | — | — | WO | disclosed |