Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11689645 | 0.85 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1ALPLRAB9ASMN1; SMN2 | |
| SCHEMBL9423222 | 0.79 | TSHR (0.41) | HSP90AB1SMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL9877761 | 0.77 | PIK3CA (0.37) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8879615 | 0.76 | POLB (0.42) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9877599 | 0.76 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1ALPLNPC1RAB9A | |
| SCHEMBL10481252 | 0.76 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1ALPLNPC1RAB9A | |
| SCHEMBL30508547 | 0.75 | CA1 (0.51) | SMN1; SMN2ALDH1A1MAPTTSHR | |
| SCHEMBL4681116 | 0.75 | CA1 (0.51) | SMN1; SMN2ALDH1A1MAPTTSHR | |
| SCHEMBL9878198 | 0.74 | CA12 (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1786163 | 0.74 | CA12 (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017211-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1991-05-21 | — | — | US | disclosed |
| EP-0333791-A1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1989-09-27 | — | — | EP | disclosed |
| WO-1989002891-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1989-04-06 | — | — | WO | disclosed |