SCHEMBL4681116

SCHEMBL4681116

CCOC(=O)c1cc(N)c(F)cc1Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.51
CA2 P00918 2/20 0.51
CA12 O43570 1/20 0.51
CA9 Q16790 1/20 0.51
CYP4F2 P78329 1/20 0.49
CYP4A11 Q02928 1/20 0.49
BAZ2B Q9UIF8 1/20 0.49
BAZ2A Q9UIF9 1/20 0.49
ALDH1A1 P00352 2/20 0.49
HSD17B10 Q99714 1/20 0.49
CYP1A2 P05177 1/20 0.48
CYP2C19 P33261 1/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
HPGD P15428 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
GAA P10253 3/20 0.46
MAPK1 P28482 1/20 0.44
TSHR P16473 1/20 0.43
KDM4E B2RXH2 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30508547 1.00 CA1 (0.51) CA1CA2CA12CA9CYP4F2
SCHEMBL29039368 0.94 CA1 (0.51) CA1CA2CA12CA9CYP4F2
SCHEMBL25286223 0.90 GAA (0.50) CA1CA2CA12CA9CYP4F2
SCHEMBL30987200 0.90 GAA (0.50) CA1CA2CA12CA9CYP4F2
SCHEMBL8879568 0.88 CYP1A2 (0.49) CA1CA2CA12CA9ALDH1A1
SCHEMBL30483130 0.88 GAA (0.43) CA1CA2CA12CA9CYP4F2
SCHEMBL9710977 0.88 ALDH1A1 (0.49) CA1CA2CA12CA9CYP4F2
SCHEMBL11951339 0.87 CA1 (0.56) CA1CA2CA12CA9CYP4F2
SCHEMBL2549970 0.87 LMNA (0.60) CA1CA2CA12CA9CYP4F2
SCHEMBL10918857 0.85 CA1 (0.55) CA1CA2CA12CA9CYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313954-B1 PREPARATION OF 2-CHLORO-4-FLUORO-5-NITROBENZOIC ACID ADAMA AGAN LTD (IL) 2025-10-15 EP disclosed
WO-2025124321-A1 PREPARATION METHOD FOR URACIL COMPOUND AND USE OF URACIL COMPOUND 江苏中旗科技股份有限公司 2025-06-19 WO disclosed
CN-119954730-A Saflufenacil herb Process for the preparation of amines 鹤壁市宝瑞德化工有限公司 2025-05-09 CN disclosed
US-20250127170-A1 TRIAZINE HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-04-24 US disclosed
US-20250115560-A1 A NEW PROCESS OF SAFLUFENACIL PRODUCTION USING NOVEL INTERMEDIATES ADAMA AGAN LTD (IL) 2025-04-10 US disclosed
US-20250109112-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-04-03 US disclosed
EP-4469443-A1 HERBICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2024-12-04 EP disclosed
EP-4452953-A1 TRIAZINE HERBICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2024-10-30 EP disclosed
CN-118591531-A Herbicidal compounds 先正达农作物保护股份公司 2024-09-03 CN disclosed
CN-118339147-A Triazine herbicidal compounds 先正达农作物保护股份公司 2024-07-12 CN disclosed
WO-1997007104-A1 PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-02-27 WO disclosed
US-5502027-A ALGICIDES ROHM AND HAAS COMPANY (US) 1996-03-26 US disclosed
EP-0415642-B1 Glutarimides ROHM & HAAS (US) 1995-12-06 EP disclosed
US-5393735-A N-(halo-oxy-)phenyl substituted cyclic imides ROHM AND HAAS COMPANY (US) 1995-02-28 US disclosed
EP-0415641-B1 Substituted glutaramic acids and derivatives ROHM & HAAS (US) 1994-01-19 EP disclosed
US-5238908-A HERBICIDAL GLUTARAMIC ACIDS AND DERIVATIVES ROHM AND HAAS COMPANY (US) 1993-08-24 US disclosed
EP-0454444-A1 Glutarimide derivatives and herbicides NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1991-10-30 EP disclosed
EP-0415641-A1 Substituted glutaramic acids and derivatives ROHM AND HAAS COMPANY (US) 1991-03-06 EP disclosed
EP-0415642-A1 Glutarimides ROHM AND HAAS COMPANY (US) 1991-03-06 EP disclosed
US-4594099-A Herbicide NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1986-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250109112-A1 HERBICIDAL COMPOUNDS DDT, ACHE, DPP7 CA1 461/4885CA2 66/4885CA12 1743/4885
US-20250115560-A1 A NEW PROCESS OF SAFLUFENACIL PRODUCTION USING NOVEL INTERMEDIATES DPYD, PDK1, CYP2S1 CA1 3673/4885CA2 3391/4885CA12 2520/4885
US-20250127170-A1 TRIAZINE HERBICIDAL COMPOUNDS DDT, DPP7, PTPRZ1 CA1 529/4885CA2 57/4885CA12 1034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.