Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10481252 | 1.00 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1ALPLNPC1RAB9A | |
| SCHEMBL9423172 | 0.80 | POLB (0.37) | NPC1RAB9ASMN1; SMN2TSHRMAPT | |
| SCHEMBL10481253 | 0.78 | POLB (0.33) | SMN1; SMN2MAPTPOLBAPEX1 | |
| SCHEMBL10916815 | 0.78 | CYP4F2 (0.47) | SMN1; SMN2TSHRMAPTMAPK1 | |
| SCHEMBL30987203 | 0.78 | KEAP1 (0.39) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL7682549 | 0.76 | GAA (0.41) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL9878081 | 0.76 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1ALPLNPC1RAB9A | |
| SCHEMBL3544332 | 0.74 | POLB (0.33) | SMN1; SMN2MAPTPOLBAPEX1 | |
| SCHEMBL9477488 | 0.73 | LMNA (0.40) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL977041 | 0.73 | HPGD (0.31) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017211-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1991-05-21 | — | — | US | disclosed |
| EP-0333791-A1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1989-09-27 | — | — | EP | disclosed |
| WO-1989002891-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1989-04-06 | — | — | WO | disclosed |