Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 5/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 2/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL604336 | 0.74 | ALDH1A1 (0.41) | ALDH1A1RAB9AGAAKMT2AGLA | |
| SCHEMBL2566141 | 0.73 | RAB9A (0.45) | ALDH1A1RAB9AGAAKMT2AGLA | |
| SCHEMBL11880471 | 0.72 | KDM4E (0.32) | ALDH1A1RAB9AGAAKMT2AGLA | |
| SCHEMBL4299906 | 0.70 | ALDH1A1 (0.70) | ALDH1A1RAB9AGAAKMT2AGLA | |
| SCHEMBL31276067 | 0.69 | ALDH1A1 (0.35) | ALDH1A1RAB9AGAAKMT2AGLA | |
| SCHEMBL13742065 | 0.68 | NPC1 (0.44) | ALDH1A1RAB9AGAAKMT2AGLA | |
| SCHEMBL10708525 | 0.67 | RAB9A (0.54) | ALDH1A1RAB9AGAAKMT2AGLA | |
| SCHEMBL30857473 | 0.66 | ALDH1A1 (0.64) | ALDH1A1RAB9AGAAKMT2AGLA | |
| SCHEMBL11905392 | 0.66 | ALDH1A1 (0.64) | ALDH1A1RAB9AGAAKMT2AGLA | |
| SCHEMBL296423 | 0.66 | ALDH1A1 (0.46) | ALDH1A1RAB9AGAAKMT2AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9287517-B2 | Functionalization of sp3 hybridized carbon, silicon and/or germanium surfaces | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2016-03-15 | — | — | US | disclosed |
| EP-2448684-B1 | FUNCTIONALIZATION OF SP3 HYBRIDIZED CARBON, SILICON, AND/OR GERMANIUM SURFACES | CENTRE NAT RECH SCIENT (FR) | 2015-12-16 | — | — | EP | disclosed |
| US-20120177894-A1 | FUNCTIONALIZATION OF SP3 HYBRIDIZED CARBON, SILICON AND/OR GERMANIUM SURFACES | UNIVERSITE JOSEPH FOURIER (FR) | 2012-07-12 | — | — | US | disclosed |
| EP-2448684-A2 | FUNCTIONALIZATION OF SP3 HYBRIDIZED CARBON, SILICON, AND/OR GERMANIUM SURFACES | Centre National de la Recherche Scientifique (C.N.R.S.) (FR) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011001123-A2 | FUNCTIONALIZATION OF SP3 HYBRIDIZED CARBON, SILICON, AND/OR GERMANIUM SURFACES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 2011-01-06 | — | — | WO | disclosed |
| US-5624924-A | Quinobenzothiazine antineoplastic agents | ABBOTT LABORATORIES (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0608215-A1 | QUINOBENZOXAZINE, QUINOBENZOTHIAZINE, AND PYRIDO-ACRIDINE ANTINEOPLASTIC AGENTS | ABBOTT LABORATORIES (US) | 1994-08-03 | — | — | EP | disclosed |
| US-5318965-A | Administering to treat leukemia, melanoma, carcinoma of lung, colon, ovaries | ABBOTT LABORATORIES (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0608215-A4 | QUINOBENZOXAZINE, QUINOBENZOTHIAZINE, AND PYRIDO-ACRIDINE ANTINEOPLASTIC AGENTS. | ABBOTT LAB (US) | 1993-11-11 | — | — | EP | disclosed |
| WO-1993016702-A1 | QUINOBENZOXAZINE, QUINOBENZOTHIAZINE, AND PYRIDO-ACRIDINE ANTINEOPLASTIC AGENTS | ABBOTT LABORATORIES (US) | 1993-09-02 | — | — | WO | disclosed |
| WO-1992003136-A1 | QUINOBENZOXAZINE, QUINOBENZOTHIAZINE, AND PYRIDO-ACRIDINE ANTINEOPLASTIC AGENTS | ABBOTT LABORATORIES (US) | 1992-03-05 | — | — | WO | disclosed |
| EP-0087951-B1 | PHENANTHROLINE DERIVATIVES | DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) | 1989-09-13 | — | — | EP | disclosed |
| US-4474961-A | ANTITUMOR AGENT | DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) | 1984-10-02 | — | — | US | disclosed |
| EP-0087951-A2 | Phenanthroline derivatives | DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) | 1983-09-07 | — | — | EP | disclosed |