Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.41 |
| ▸ | CA1 | P00915 | 11/20 | 0.41 |
| ▸ | CA12 | O43570 | 9/20 | 0.41 |
| ▸ | CA9 | Q16790 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877380 | 0.90 | CA2 (0.41) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL10913759 | 0.85 | CA2 (0.39) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL7034225 | 0.81 | ALDH1A1 (0.47) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL8516324 | 0.80 | CA2 (0.47) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL10898587 | 0.80 | ALDH1A1 (0.37) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL27785864 | 0.79 | ALDH1A1 (0.45) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL8864908 | 0.78 | ALDH1A1 (0.46) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL7031844 | 0.77 | ALDH1A1 (0.46) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL4528062 | 0.75 | KMT2A (0.49) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL10803250 | 0.75 | ALDH1A1 (0.47) | CA2CA1CA12CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |
| EP-0171611-A1 | Substituted phenyloxethyl sulphones and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-02-19 | — | — | EP | disclosed |