Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | ALPL | P05186 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 8/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29202204 | 0.83 | PIK3CA (0.42) | CAPN1ALDH1A1KDM4EHSD17B10ALPL | |
| SCHEMBL30703081 | 0.75 | DRD4 (0.58) | ALDH1A1KDM4EHSD17B10ALPLMAPT | |
| SCHEMBL2706251 | 0.75 | DRD4 (0.58) | ALDH1A1KDM4EHSD17B10ALPLMAPT | |
| SCHEMBL182207 | 0.73 | CAPN1 (0.44) | CAPN1ALDH1A1KDM4EHSD17B10ALPL | |
| SCHEMBL182119 | 0.70 | MAOA (0.43) | CAPN1ALDH1A1KDM4EHSD17B10ALPL | |
| SCHEMBL8578857 | 0.69 | MAPT (0.45) | CAPN1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL14059503 | 0.66 | KMT2A (0.47) | ALDH1A1KDM4EHSD17B10ALPLMAPT | |
| SCHEMBL4815082 | 0.65 | MAPT (0.48) | ALDH1A1KDM4EHSD17B10ALPLMAPT | |
| SCHEMBL8580886 | 0.65 | PIK3CA (0.40) | CAPN1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL2548370 | 0.65 | MAPT (0.62) | ALDH1A1KDM4EHSD17B10ALPLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991012255-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-22 | — | — | WO | disclosed |