SCHEMBL987908

SCHEMBL987908

O=C1C=C(c2ccccc2)C(=O)C(c2ccccc2)=C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 7/20 1.00
MAOA P21397 1/20 0.60
MAOB P27338 1/20 0.60
PTPN1 P18031 5/20 0.56
PTPRC P08575 2/20 0.56
PTPRF P10586 1/20 0.56
CDC25B P30305 1/20 0.56
HSD17B3 P37058 1/20 0.56
PDE4B Q07343 2/20 0.47
MAPT P10636 2/20 0.42
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42
ALDH1A1 P00352 2/20 0.40
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
ALOX12 P18054 1/20 0.38
CCR6 P51684 1/20 0.38
CACNA1B Q00975 1/20 0.38
APBA1 Q02410 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8407139 0.87 BACE1 (0.76) BACE1MAOAMAOBPTPN1PTPRC
SCHEMBL8406792 0.87 BACE1 (0.76) BACE1MAOAMAOBPTPN1PTPRC
SCHEMBL26135886 0.86 BACE1 (0.76) BACE1MAOAMAOBPTPN1PTPRC
SCHEMBL11299155 0.85 BACE1 (0.73) BACE1MAOAMAOBPTPN1PTPRC
SCHEMBL10438716 0.84 BACE1 (0.72) BACE1MAOAMAOBPTPN1PTPRC
SCHEMBL134702 0.84 BACE1 (0.73) BACE1MAOAMAOBPTPN1PTPRC
SCHEMBL9453987 0.80 BACE1 (0.64) BACE1MAOAMAOBPTPN1PTPRC
SCHEMBL9454008 0.80 BACE1 (0.64) BACE1MAOAMAOBPTPN1PTPRC
SCHEMBL5531506 0.78 BACE1 (0.64) BACE1MAOAMAOBPTPN1PTPRC
Benzene SCHEMBL28365226 0.77 BACE1 (0.61) BACE1MAOAMAOBPTPN1PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2449561-A2 POLYMERS COMPRISING AT LEAST ONE BITHIOPHENE REPEAT UNIT, METHODS SYNTHETISING SAID POLYMERS AND COMPOSITIONS COMPRISING THE SAME Plextronics, Inc. (US) 2012-05-09 EP claimed
WO-2011002927-A2 NOVEL COMPOSITIONS, METHODS AND POLYMERS PLEXTRONICS, INC. (US) 2011-01-06 WO claimed
US-7368624-B2 Reacting arene hydrocarbon with an organic oxidant selected fromquinone, a quinone imine, a quinone diimine, or a nitroarene, in the presence of a Bronsted or Lewis acid, in absence of free halogen impurities; quenching the reaction with a organic or organometallic compound EASTMAN KODAK COMPANY (US) 2008-05-06 US claimed
WO-2005100286-A2 SYNTHESIS FOR POLYCYCLIC AROMATIC HYDROCARBON COMPOUNDS EASTMAN KODAK COMPANY (US) 2005-10-27 WO claimed
US-20050222417-A1 Synthesis for polycyclic aromatic hydrocarbon compounds EASTMAN KODAK COMPANY 2005-10-06 US claimed
EP-0301003-B1 MODIFIED POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1991-01-02 EP claimed
EP-0301003-A1 MODIFIED POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS. GEN ELECTRIC (US) 1989-02-01 EP claimed
WO-1988006172-A1 MODIFIED POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1988-08-25 WO claimed
US-4659763-A QUINONE MODIFIERS FOR IMPACT STRENGTH, ELONGATION GENERAL ELECTRIC COMPANY (US) 1987-04-21 US claimed
WO-2024135708-A1 METHOD FOR PRODUCING COMPOUND, POLYMER, COMPOSITION, AND PATTERN FORMATION METHOD 三菱瓦斯化学株式会社 2024-06-27 WO disclosed
US-8440785-B2 Compositions, methods and polymers PLEXTRONICS, INC. (US) 2013-05-14 US disclosed
EP-2449561-A2 POLYMERS COMPRISING AT LEAST ONE BITHIOPHENE REPEAT UNIT, METHODS SYNTHETISING SAID POLYMERS AND COMPOSITIONS COMPRISING THE SAME Plextronics, Inc. (US) 2012-05-09 EP disclosed
US-20110028644-A1 NOVEL COMPOSITIONS, METHODS AND POLYMERS PLEXTRONICS, INC. 2011-02-03 US disclosed
WO-2011002927-A2 NOVEL COMPOSITIONS, METHODS AND POLYMERS PLEXTRONICS, INC. (US) 2011-01-06 WO disclosed
EP-0301004-A1 POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1989-02-01 EP disclosed
WO-1988006172-A1 MODIFIED POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1988-08-25 WO disclosed
WO-1988006173-A1 POLYPHENYLENE ETHER POLYAMIDE BLENDS GENERAL ELECTRIC COMPANY (US) 1988-08-25 WO disclosed
WO-1988006168-A1 POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1988-08-25 WO disclosed
US-4659763-A QUINONE MODIFIERS FOR IMPACT STRENGTH, ELONGATION GENERAL ELECTRIC COMPANY (US) 1987-04-21 US disclosed
US-4360469-A Preparation of quinones by salcomine-catalyzed oxidation of phenols EASTMAN KODAK COMPANY (US) 1982-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050222417-A1 Synthesis for polycyclic aromatic hydrocarbon compounds PAH, AHR, NQO1 BACE1 4292/4885MAOA 145/4885MAOB 117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.