SCHEMBL134702

SCHEMBL134702

O=C1C(c2ccccc2)=CC(=C2C=C(c3ccccc3)C(=O)C(c3ccccc3)=C2)C=C1c1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 7/20 0.73
PTPN1 P18031 3/20 0.56
PTPRC P08575 3/20 0.56
CDC25B P30305 2/20 0.56
PTPRF P10586 1/20 0.56
MAOA P21397 2/20 0.48
MAOB P27338 1/20 0.48
PDE4B Q07343 1/20 0.47
HSD17B3 P37058 1/20 0.45
LMNA P02545 3/20 0.42
MAPT P10636 3/20 0.42
HTT P42858 3/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
APAF1 O14727 2/20 0.40
NPC1 O15118 2/20 0.40
THRB P10828 2/20 0.40
RAB9A P51151 2/20 0.40
GALK1 P51570 2/20 0.40
BLM P54132 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10160580 0.87 BACE1 (0.57) BACE1PTPN1PTPRCCDC25BPTPRF
SCHEMBL16601801 0.87 BACE1 (0.57) BACE1PTPN1PTPRCCDC25BPTPRF
SCHEMBL987908 0.84 BACE1 (1.00) BACE1PTPN1PTPRCCDC25BPTPRF
SCHEMBL16601629 0.80 BACE1 (0.48) BACE1PTPN1PTPRCCDC25BPTPRF
SCHEMBL5531506 0.78 BACE1 (0.64) BACE1PTPN1PTPRCCDC25BPTPRF
SCHEMBL5485068 0.77 BACE1 (1.00) BACE1PTPN1PTPRCCDC25BPTPRF
SCHEMBL12677689 0.77 BACE1 (0.70) BACE1PTPN1PTPRCCDC25BPTPRF
SCHEMBL29673492 0.77 BACE1 (1.00) BACE1PTPN1PTPRCCDC25BPTPRF
SCHEMBL8407139 0.73 BACE1 (0.76) BACE1PTPN1PTPRCCDC25BPTPRF
SCHEMBL8406792 0.73 BACE1 (0.76) BACE1PTPN1PTPRCCDC25BPTPRF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9760029-B2 Electrophotographic photosensitive member, image forming apparatus, and process cartridge KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-09-12 US disclosed
US-9760029-B2 Electrophotographic photosensitive member, image forming apparatus, and process cartridge KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-09-12 US disclosed
US-20160223923-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-08-04 US disclosed
US-20160223923-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-08-04 US disclosed
EP-3051352-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER AND METHOD FOR MANUFACTURING THE SAME, AND IMAGE FORMING APPARATUS Kyocera Document Solutions Inc. (JP) 2016-08-03 EP disclosed
US-8384286-B2 Compound and organic light emitting device using the compound CANON KABUSHIKI KAISHA (JP) 2013-02-26 US disclosed
US-8384286-B2 Compound and organic light emitting device using the compound CANON KABUSHIKI KAISHA (JP) 2013-02-26 US disclosed
US-8288017-B2 Fused ring aromatic compound and organic light-emitting device using same CANON KABUSHIKI KAISHA (JP) 2012-10-16 US disclosed
US-8288017-B2 Fused ring aromatic compound and organic light-emitting device using same CANON KABUSHIKI KAISHA (JP) 2012-10-16 US disclosed
US-8263235-B2 High light extraction efficiency and good in an light emitting efficiency and durability CANON KABUSHIKI KAISHA (JP) 2012-09-11 US disclosed
US-20080119671-A1 PYRENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2008-05-22 US disclosed
US-7338721-B2 Condensed polycyclic compound and organic light-emitting device using the same CANON KABUSHIKI KAISHA (JP) 2008-03-04 US disclosed
US-7338721-B2 Condensed polycyclic compound and organic light-emitting device using the same CANON KABUSHIKI KAISHA (JP) 2008-03-04 US disclosed
WO-2007114038-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE COMPOUND CANON KABUSHIKI KAISHA (JP) 2007-10-11 WO disclosed
US-7241513-B2 Fluorene compound and organic luminescent device using the same CANON KABUSHIKI KAISHA (JP) 2007-07-10 US disclosed
US-7241513-B2 Fluorene compound and organic luminescent device using the same CANON KABUSHIKI KAISHA (JP) 2007-07-10 US disclosed
US-7232618-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2007-06-19 US disclosed
US-7232618-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2007-06-19 US disclosed
US-7229702-B2 Oligofluorenlylene compounds CANON KABUSHIKI KAISHA (JP) 2007-06-12 US disclosed
US-7229702-B2 Oligofluorenlylene compounds CANON KABUSHIKI KAISHA (JP) 2007-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080119671-A1 PYRENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE AHR, CYP1A1, ARNT BACE1 926/4885PTPN1 4169/4885PTPRC 4666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.