Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 7/20 | 0.73 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.44 |
| ▸ | PTPRC | P08575 | 2/20 | 0.44 |
| ▸ | PTPRF | P10586 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL987908 | 0.85 | BACE1 (1.00) | BACE1MAOAMAOBPTPN1PTPRC | |
| SCHEMBL8407139 | 0.74 | BACE1 (0.76) | BACE1MAOAMAOBPTPN1PTPRC | |
| SCHEMBL8406792 | 0.74 | BACE1 (0.76) | BACE1MAOAMAOBPTPN1PTPRC | |
| SCHEMBL26135886 | 0.74 | BACE1 (0.76) | BACE1MAOAMAOBPTPN1PTPRC | |
| SCHEMBL10438716 | 0.72 | BACE1 (0.72) | BACE1MAOAMAOBPTPN1PTPRC | |
| SCHEMBL134702 | 0.72 | BACE1 (0.73) | BACE1MAOAMAOBPTPN1PTPRC | |
| Biphenyl SCHEMBL936186 | 0.71 | ALDH1A1 (0.60) | MAOAALDH1A1 | |
| SCHEMBL27519851 | 0.71 | MAOA (0.84) | BACE1MAOAMAOBPTPN1PTPRC | |
| SCHEMBL11300666 | 0.69 | ALOX5 (0.43) | — | |
| SCHEMBL9454008 | 0.68 | BACE1 (0.64) | BACE1MAOAMAOBPTPN1PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4280819-A | FUEL ADDITIVES ALSO FOR JET FUELS | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1981-07-28 | — | — | US | disclosed |