Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | PDE9A | O76083 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879095 | 0.83 | MEN1 (0.54) | MEN1KMT2AGAAMAPTPDE9A | |
| SCHEMBL9879379 | 0.80 | MEN1 (0.64) | MEN1KMT2AGAANAMPTMAPT | |
| SCHEMBL9879088 | 0.79 | GAA (0.75) | MEN1KMT2AGAANAMPTMAPT | |
| SCHEMBL9879255 | 0.78 | MEN1 (0.55) | MEN1KMT2AGAANAMPTMAPT | |
| SCHEMBL9879390 | 0.78 | MEN1 (0.61) | MEN1KMT2AGAAMAPTPDE9A | |
| SCHEMBL9879258 | 0.76 | MAPT (0.62) | MEN1KMT2AGAANAMPTMAPT | |
| SCHEMBL9878162 | 0.76 | MEN1 (0.52) | MEN1KMT2AGAANAMPTMAPT | |
| SCHEMBL9878159 | 0.76 | MEN1 (0.52) | MEN1KMT2AGAANAMPTMAPT | |
| SCHEMBL2495430 | 0.76 | MAPK1 (0.57) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL17226741 | 0.75 | MAPT (0.49) | MEN1KMT2AGAAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018887-A1 | DIAMINOPYRIMIDINE COMPOUNDS | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1991-12-12 | — | — | WO | disclosed |