Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 9/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 5/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721240 | 0.84 | KDM4E (0.42) | KDM4EPPARGPPARANPSR1MEN1 | |
| SCHEMBL9878823 | 0.82 | PPARG (0.42) | LIPGMAOACISD1PPARGFFAR1 | |
| SCHEMBL10480785 | 0.78 | PPARG (0.40) | KDM4EPPARGPPARANPSR1MEN1 | |
| SCHEMBL131888 | 0.78 | PPARG (0.55) | PPARGFFAR1PPARAMEN1MAPT | |
| SCHEMBL9274342 | 0.76 | PPARG (0.47) | PPARGFFAR1PPARA | |
| SCHEMBL7879128 | 0.76 | PPARG (0.47) | PPARGFFAR1PPARA | |
| SCHEMBL7877640 | 0.76 | PPARG (0.47) | PPARGFFAR1PPARA | |
| SCHEMBL9286066 | 0.76 | PPARG (0.47) | PPARGFFAR1PPARA | |
| SCHEMBL7877637 | 0.76 | PPARG (0.47) | PPARGFFAR1PPARA | |
| SCHEMBL8116286 | 0.76 | PPARG (0.45) | PPARGFFAR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991003474-A1 | HYPOGLYCEMIC THIAZOLIDINEDIONE DERIVATIVES | PFIZER INC. (US) | 1991-03-21 | — | — | WO | disclosed |