Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.45 |
| ▸ | PPARA | Q07869 | 9/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131888 | 0.89 | PPARG (0.55) | PPARGPPARACYP3A4FFAR1 | |
| SCHEMBL9878823 | 0.85 | PPARG (0.42) | PPARGPPARACYP3A4RXRAFFAR1 | |
| SCHEMBL8116894 | 0.82 | PPARG (0.48) | PPARGPPARACYP3A4RXRAFFAR1 | |
| SCHEMBL10366694 | 0.81 | MAOB (0.47) | PPARGPPARACYP3A4FFAR1 | |
| SCHEMBL8323757 | 0.81 | PPARG (0.46) | PPARGPPARACYP3A4RXRAFFAR1 | |
| SCHEMBL2572355 | 0.79 | PPARG (0.58) | PPARGPPARACYP3A4RXRAFFAR1 | |
| SCHEMBL9520977 | 0.78 | PPARG (0.45) | PPARGPPARA | |
| SCHEMBL8163904 | 0.78 | PPARG (0.39) | PPARGPPARACYP3A4 | |
| SCHEMBL10365707 | 0.76 | PPARG (0.61) | PPARGPPARACYP3A4RXRAFFAR1 | |
| SCHEMBL9879239 | 0.76 | LIPG (0.38) | PPARGPPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751944-B1 | THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS | NISSAN CHEMICAL IND LTD (JP) | 2000-12-20 | — | — | EP | disclosed |
| US-5955481-A | Pyridine type thiazolidines | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |
| WO-1995026347-A1 | THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-05 | — | — | WO | disclosed |