SCHEMBL9879243

SCHEMBL9879243

CCCc1cc(=O)nc(N)[nH]1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.54
ADORA1 P30542 2/20 0.49
MPO P05164 1/20 0.44
TPO P07202 1/20 0.44
TSHR P16473 1/20 0.44
LPO P22079 1/20 0.44
CYP2C19 P33261 1/20 0.44
TAS2R38 P59533 1/20 0.44
ADORA2A P29274 1/20 0.43
KDM4E B2RXH2 3/20 0.41
ABL1 P00519 1/20 0.41
RIN1 Q13671 1/20 0.41
GPR84 Q9NQS5 6/20 0.40
ALDH1A1 P00352 2/20 0.39
HPGD P15428 2/20 0.39
RAB9A P51151 1/20 0.39
MAPK10 P53779 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HCAR2 Q8TDS4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1123602 0.86 GPR84 (0.58) GPR84
SCHEMBL1123403 0.86 GPR84 (0.58) GPR84
SCHEMBL3723702 0.85 BACE1 (0.44) BACE1ADORA1KDM4EABL1RIN1
SCHEMBL12342674 0.80 BACE1 (0.38) BACE1ADORA1TSHRKDM4EALDH1A1
SCHEMBL23542304 0.79 ADORA1 (0.47) BACE1ADORA1MPOTPOTSHR
SCHEMBL3724930 0.79 BACE1 (0.40) BACE1KDM4EABL1RIN1ALDH1A1
Propylthiouracil SCHEMBL17375339 0.78 MPO (0.44) BACE1ADORA1MPOTPOTSHR
SCHEMBL12936008 0.77 NPSR1 (0.37) BACE1ADORA1KDM4EABL1RIN1
SCHEMBL25036350 0.77 ADORA1 (0.46) BACE1ADORA1MPOTPOTSHR
SCHEMBL10617517 0.77 CYP3A4 (0.41) BACE1KDM4EABL1RIN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116655934-A Crystalline polymer containing quadruple hydrogen bonds and preparation method thereof 上海大学 2023-08-29 CN claimed
CN-116655934-B Crystalline polymer containing quadruple hydrogen bonds and preparation method thereof 上海大学 2025-07-15 CN disclosed
CN-116655934-A Crystalline polymer containing quadruple hydrogen bonds and preparation method thereof 上海大学 2023-08-29 CN disclosed
CN-116655934-A Crystalline polymer containing quadruple hydrogen bonds and preparation method thereof 上海大学 2023-08-29 CN disclosed
WO-1991018887-A1 DIAMINOPYRIMIDINE COMPOUNDS SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) 1991-12-12 WO disclosed