Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 8/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57085 | 0.84 | NFE2L2 (0.58) | NFE2L2CYP1A1CYP1A2CYP1B1PRMT1 | |
| SCHEMBL8693298 | 0.82 | NFE2L2 (0.52) | NFE2L2CYP1A1CYP1A2CYP1B1CYP19A1 | |
| SCHEMBL27702145 | 0.81 | NFE2L2 (0.60) | NFE2L2CYP1A1CYP1A2CYP1B1PRMT1 | |
| SCHEMBL118591 | 0.79 | NFE2L2 (0.79) | NFE2L2CYP1A1CYP1A2CYP1B1PRMT1 | |
| SCHEMBL1590638 | 0.79 | NFE2L2 (0.61) | NFE2L2CYP1A1CYP1A2CYP1B1PRMT1 | |
| SCHEMBL1546324 | 0.78 | NFE2L2 (0.59) | NFE2L2CYP1A1CYP1A2CYP1B1PRMT1 | |
| SCHEMBL1045609 | 0.77 | NFE2L2 (0.64) | NFE2L2CYP1A1CYP1A2CYP1B1PRMT1 | |
| SCHEMBL1045608 | 0.77 | NFE2L2 (0.64) | NFE2L2CYP1A1CYP1A2CYP1B1PRMT1 | |
| SCHEMBL4642599 | 0.76 | NFE2L2 (0.58) | NFE2L2CYP1A1CYP1A2CYP1B1PRMT1 | |
| O-Veratraldehyde SCHEMBL29923149 | 0.76 | SRC (0.67) | NFE2L2CYP1A1CYP1A2CYP1B1PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034418-A | Anticoagulants | EISAI CO., LTD. (JP) | 1991-07-23 | — | — | US | claimed |
| US-4391821-A | HYPOTENSIVE AGENTS, ADRENERGIC BLOCKING AGENTS, ANTIARRHYTHMIA AGENTS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1983-07-05 | — | — | US | claimed |
| US-4391821-A | HYPOTENSIVE AGENTS, ADRENERGIC BLOCKING AGENTS, ANTIARRHYTHMIA AGENTS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1983-07-05 | — | — | US | disclosed |