Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 13/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 8/20 | 0.48 |
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | PER2 | O15055 | 1/20 | 0.42 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519276 | 0.93 | TBXA2R (0.67) | TBXA2RTBXAS1PDE2AAKR1B1PTGDR | |
| SCHEMBL9518784 | 0.90 | TBXA2R (0.54) | TBXA2RTBXAS1AKR1B1PTGDRPTGDR2 | |
| SCHEMBL9521310 | 0.83 | TBXA2R (0.64) | TBXA2RPDE2APTGDR | |
| SCHEMBL9518398 | 0.82 | PTGDR (0.48) | TBXA2RPDE2APTGDRPTGDR2 | |
| SCHEMBL9518525 | 0.81 | TBXA2R (0.52) | TBXA2RPDE2AAKR1B10AKR1A1AKR1B1 | |
| SCHEMBL9518789 | 0.81 | TBXA2R (0.69) | TBXA2RTBXAS1PDE2AAKR1B1PTGDR | |
| SCHEMBL9879388 | 0.81 | TBXA2R (0.58) | TBXA2RTBXAS1PDE2AAKR1B10AKR1A1 | |
| SCHEMBL9518853 | 0.79 | TBXA2R (0.85) | TBXA2RTBXAS1PDE2APTGDR | |
| SCHEMBL9518380 | 0.78 | TBXA2R (0.67) | TBXA2RTBXAS1PDE2APTGDRPTGDR2 | |
| SCHEMBL7248571 | 0.78 | PDE2A (0.68) | TBXA2RPDE2APTGDRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239306-B1 | TETRAHYDROCARBAZOLE ESTERS | MERCK FROSST CANADA INC. (CA) | 1993-06-02 | — | — | EP | claimed |