Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | UGCG | Q16739 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10764616 | 1.00 | TP53 (0.47) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL9449144 | 0.99 | LMNA (0.46) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL9449462 | 0.99 | LMNA (0.46) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL9449296 | 0.99 | LMNA (0.46) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL9449024 | 0.99 | LMNA (0.46) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL9449361 | 0.99 | LMNA (0.46) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL9449061 | 0.99 | LMNA (0.46) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL9448976 | 0.97 | RAB9A (0.45) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL9449268 | 0.91 | RAB9A (0.49) | UGCGRAB9AALDH1A1HTTNPC1 | |
| Hydrochloric Acid SCHEMBL9449083 | 0.90 | RAB9A (0.50) | UGCGRAB9AALDH1A1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177245-B1 | AMINO-ALCOHOL DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-04-10 | — | — | EP | disclosed |