Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHAT | P28329 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1207128 | 0.88 | ALDH1A1 (0.62) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| Styrene SCHEMBL27829265 | 0.86 | ALDH1A1 (0.64) | ALDH1A1TSHRTDP1NPC1POLB | |
| Styrene SCHEMBL27325031 | 0.86 | ALDH1A1 (0.64) | ALDH1A1TSHRTDP1NPC1POLB | |
| Styrene SCHEMBL7556859 | 0.84 | ALDH1A1 (0.78) | ALDH1A1TSHRNPC1POLBMAPT | |
| Styrene SCHEMBL27756866 | 0.84 | ALDH1A1 (0.61) | ALDH1A1TSHRTDP1NPC1POLB | |
| SCHEMBL9814638 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| Styrene SCHEMBL28849678 | 0.82 | ALDH1A1 (0.75) | ALDH1A1TSHRNPC1POLBMAPT | |
| Styrene SCHEMBL28033916 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| Styrene SCHEMBL28220741 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| Styrene SCHEMBL10790034 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985414-A | DETERMINATION OF PHOSPHATASE ENZYME | BOEHRINGER MANNHEIM GMBH (DE) | 1991-01-15 | — | — | US | disclosed |