Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15540594 | 0.67 | HTR2C (0.55) | HTR2CHTR2AHTR2BKDM1ACES2 | |
| SCHEMBL5318529 | 0.65 | KDM1A (0.43) | HTR2CHTR2AHTR2BKDM1ARCOR1 | |
| Hydrochloric Acid SCHEMBL30882422 | 0.64 | F2 (0.52) | HTR2CHTR2AHTR2BKDM1ARCOR1 | |
| SCHEMBL171684 | 0.64 | CES2 (0.71) | CES2PARP1 | |
| SCHEMBL27621589 | 0.64 | CES2 (0.71) | CES2PARP1 | |
| SCHEMBL16892940 | 0.64 | CES2 (0.55) | CES2KIF11 | |
| SCHEMBL10601313 | 0.64 | HTR2C (0.50) | HTR2CHTR2AHTR2BKDM1ACES2 | |
| SCHEMBL30532337 | 0.63 | HTR2C (0.53) | HTR2CHTR2AHTR2BAKT1TRPM5 | |
| SCHEMBL21296542 | 0.63 | HTR2C (0.54) | HTR2CHTR2AHTR2BGUSB | |
| Hydrochloric Acid SCHEMBL4372373 | 0.63 | CES2 (0.69) | CES2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059599-A | Anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1991-10-22 | — | — | US | disclosed |