Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22832180 | 0.91 | MEN1 (0.44) | MGAMGAASIMGAM2SMN1; SMN2 | |
| SCHEMBL9879788 | 0.89 | HDAC4 (0.50) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL28554675 | 0.87 | APP (0.46) | MGAMGAASIMGAM2SMN1; SMN2 | |
| SCHEMBL196440 | 0.84 | MGAM (0.55) | MGAMGAASIMGAM2SMN1; SMN2 | |
| SCHEMBL30491272 | 0.82 | TOP1 (0.52) | MGAMGAASIMGAM2SMN1; SMN2 | |
| SCHEMBL476858 | 0.81 | APP (0.57) | SMN1; SMN2TOP1KDM4EALDH1A1APP | |
| SCHEMBL735693 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4EALDH1A1TP53MAPT | |
| SCHEMBL16674078 | 0.80 | CA1 (0.55) | MGAMGAASIMGAM2SMN1; SMN2 | |
| SCHEMBL29174503 | 0.79 | APP (0.50) | SMN1; SMN2KDM4EALDH1A1APPMAPT | |
| Hydrochloric Acid SCHEMBL28639461 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4EALDH1A1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2735581-B1 | COMPOSITION AND POLYMER | ASAHI CHEMICAL IND (JP) | 2021-07-14 | — | — | EP | disclosed |
| US-9738757-B2 | Composition and polymer | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2017-08-22 | — | — | US | disclosed |
| US-20160222168-A1 | Composition and Polymer | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-08-04 | — | — | US | disclosed |
| US-9334371-B2 | Composition and polymer | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-05-10 | — | — | US | disclosed |
| EP-2735581-A1 | COMPOSITION AND POLYMER | Asahi Kasei Chemicals Corporation (JP) | 2014-05-28 | — | — | EP | disclosed |
| US-20140121293-A1 | Composition and Polymer | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2014-05-01 | — | — | US | disclosed |
| US-5049693-A | Process for the selective hydrogenation of olefins containing nitrile groups | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-17 | — | — | US | disclosed |