SCHEMBL196440

SCHEMBL196440

COc1cccc(-c2cccc(OC)c2OC)c1OC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.55
GAA P10253 1/20 0.55
SI P14410 1/20 0.55
MGAM2 Q2M2H8 1/20 0.55
SMN1; SMN2 Q16637 6/20 0.54
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA4 P22748 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
KDM4E B2RXH2 4/20 0.49
ALDH1A1 P00352 4/20 0.49
TDP1 Q9NUW8 1/20 0.49
TP53 P04637 4/20 0.47
MAPT P10636 4/20 0.47
RAB9A P51151 4/20 0.47
NPC1 O15118 3/20 0.47
HSD17B10 Q99714 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16674078 0.95 CA1 (0.55) MGAMGAASIMGAM2SMN1; SMN2
SCHEMBL30491272 0.88 TOP1 (0.52) MGAMGAASIMGAM2SMN1; SMN2
SCHEMBL21877426 0.87 P2RX7 (0.51) MGAMGAASIMGAM2SMN1; SMN2
SCHEMBL27318706 0.87 CA12 (0.46) MGAMGAASIMGAM2SMN1; SMN2
SCHEMBL6536005 0.87 KDM4E (0.57) MGAMGAASIMGAM2SMN1; SMN2
SCHEMBL12945567 0.87 CA12 (0.46) MGAMGAASIMGAM2SMN1; SMN2
SCHEMBL13732793 0.87 GAA (0.54) MGAMGAASIMGAM2SMN1; SMN2
SCHEMBL25434306 0.86 CA1 (0.61) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL151213 0.86 CA1 (0.61) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL27753904 0.86 CA1 (0.61) SMN1; SMN2CA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11053188-B2 Process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides SYNGENTA PARTICIPATIONS AG (CH) 2021-07-06 US claimed
US-20200407311-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES SYNGENTA PARTICIPATIONS AG (CH) 2020-12-31 US claimed
CN-108400379-A A kind of preparation of the preparation method and full battery of high security lithium ion battery diaphragm 北京大学 2018-08-14 CN claimed
US-20210403636-A1 POLYEPOXIDIZED BIPHENYL COMPOUNDS, PREPARATION AND USES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2021-12-30 US disclosed
US-11053188-B2 Process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides SYNGENTA PARTICIPATIONS AG (CH) 2021-07-06 US disclosed
US-20200407311-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES SYNGENTA PARTICIPATIONS AG (CH) 2020-12-31 US disclosed
CN-108400379-A A kind of preparation of the preparation method and full battery of high security lithium ion battery diaphragm 北京大学 2018-08-14 CN disclosed
US-9045582-B2 Cross-linked rubbery polyurethane-ether membranes for separations UOP LLC (US) 2015-06-02 US disclosed
US-9045582-B2 Cross-linked rubbery polyurethane-ether membranes for separations UOP LLC (US) 2015-06-02 US disclosed
US-20150114224-A1 CROSS-LINKED RUBBERY POLYURETHANE-ETHER MEMBRANES FOR SEPARATIONS UOP LLC (US) 2015-04-30 US disclosed
US-20150114224-A1 CROSS-LINKED RUBBERY POLYURETHANE-ETHER MEMBRANES FOR SEPARATIONS UOP LLC (US) 2015-04-30 US disclosed
US-20100310512-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2010-12-09 US disclosed
US-20100292481-A1 METHOD FOR PRODUCING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED 2010-11-18 US disclosed
EP-2233459-A1 METHOD FOR PRODUCING CONJUGATED AROMATIC COMPOUND Sumitomo Chemical Company, Limited (JP) 2010-09-29 EP disclosed
US-20100184978-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-22 US disclosed
EP-2192124-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND WITH THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-06-02 EP disclosed
EP-2172470-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-04-07 EP disclosed
WO-2006093467-A1 CONJUGATED ORGANIC MOLECULES FOR MOLECULAR ELECTRONIC DEVICES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2006-09-08 WO disclosed
EP-0670856-A1 THERMOSETTABLE COMPOSITION CONTAINING MESOGENIC MOIETIES THE DOW CHEMICAL COMPANY (US) 1995-09-13 EP disclosed
WO-1994012556-A2 THERMOSETTABLE COMPOSITION CONTAINING DISCOTIC MESOGENIC MOIETIES THE DOW CHEMICAL COMPANY (US) 1994-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100184978-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX C9, C5, AP2M1 MGAM 4661/4885GAA 4519/4885SI 4578/4885
US-20200407311-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES TBCB, ADORA2B, ADRA2B MGAM 2496/4885GAA 2604/4885SI 2459/4885
US-20100292481-A1 METHOD FOR PRODUCING CONJUGATED AROMATIC COMPOUND TYR, PAH, AHR MGAM 4138/4885GAA 1260/4885SI 1875/4885
US-20210403636-A1 POLYEPOXIDIZED BIPHENYL COMPOUNDS, PREPARATION AND USES CYP1B1, PCBP1, CYP1A1 MGAM 2378/4885GAA 1890/4885SI 3876/4885
US-11053188-B2 Process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides TBCB, ADORA2B, CCNB3 MGAM 2439/4885GAA 2515/4885SI 2494/4885
US-20100310512-A1 ANTIVIRAL COMPOUNDS MAVS, EIF2AK2, ZC3HAV1 MGAM 2953/4885GAA 151/4885SI 1414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.