SCHEMBL476858

SCHEMBL476858

COc1ccccc1-c1cccc(P)c1-c1ccccc1OC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.57
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
ALDH1A1 P00352 4/20 0.44
HTR7 P34969 4/20 0.43
TOP1 P11387 1/20 0.43
KDM4E B2RXH2 2/20 0.42
MEN1 O00255 1/20 0.42
USP2 O75604 1/20 0.42
MAPT P10636 1/20 0.42
DUSP3 P51452 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29174505 0.90 APP (0.59) APPCA12CA1CA2CA4
SCHEMBL28200391 0.88 APP (0.49) APPCA12CA1CA2CA4
SCHEMBL28200388 0.88 APP (0.49) APPCA12CA1CA2CA4
SCHEMBL30863760 0.86 APP (0.50) APPCA12CA1CA2CA4
SCHEMBL9014143 0.85 APP (0.57) APPCA12CA1CA2CA4
SCHEMBL28382893 0.83 APP (0.55) APPCA12CA1CA2CA4
SCHEMBL2021959 0.83 KCNH2 (0.40) APPTOP1STK10SLK
SCHEMBL29174503 0.82 APP (0.50) APPCA12CA1CA2CA4
SCHEMBL365363 0.82 TOP1 (0.48) APPCA12CA1CA2CA4
SCHEMBL21349009 0.81 CA1 (0.52) APPCA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2321244-B1 IMPROVED PROCESS FOR TELOMERIZATION OF BUTADIENE DOW GLOBAL TECHNOLOGIES LLC (US) 2016-12-21 EP claimed
US-8558030-B2 Process for telomerization of butadiene DOW GLOBAL TECHNOLOGIES LLC (US) 2013-10-15 US claimed
US-20110137086-A1 PROCESS FOR TELOMERIZATION OF BUTADIENE Dow Global Technologies LLC (Formerly known as Dow Global Technologies Inc.) (US) 2011-06-09 US claimed
EP-2321244-A2 AN IMPROVED PROCESS FOR TELOMERIZATION OF BUTADIENE Dow Global Technologies LLC (US) 2011-05-18 EP claimed
WO-2010019360-A2 AN IMPROVED PROCESS FOR TELOMERIZATION OF BUTADIENE DOW GLOBAL TECHNOLOGIES INC. (US) 2010-02-18 WO claimed
US-12617952-B1 Self-ameliorate-fissure-responsive pod system for alkyd-polyester aircraft runway paint UNIVERSITY OF TABUK (SA) 2026-05-05 US disclosed
EP-4101892-B1 COMPOSITION, THERMALLY CONDUCTIVE MATERIAL, THERMALLY CONDUCTIVE SHEET, AND DEVICE WITH THERMALLY CONDUCTIVE LAYER FUJIFILM CORP (JP) 2024-02-21 EP disclosed
US-20230020941-A1 COMPOSITION, THERMALLY CONDUCTIVE MATERIAL, THERMALLY CONDUCTIVE SHEET, AND DEVICE WITH THERMALLY CONDUCTIVE LAYER FUJIFILM CORPORATION (JP) 2023-01-19 US disclosed
EP-4101892-A1 COMPOSITION, THERMALLY CONDUCTIVE MATERIAL, THERMALLY CONDUCTIVE SHEET, AND DEVICE WITH THERMALLY CONDUCTIVE LAYER FUJIFILM Corporation (JP) 2022-12-14 EP disclosed
EP-2735581-B1 COMPOSITION AND POLYMER ASAHI CHEMICAL IND (JP) 2021-07-14 EP disclosed
US-9988373-B2 Nitrogen-containing six-membered cyclic derivatives and pharmaceutical composition comprising the same SHIONOGI & CO., LTD. (JP) 2018-06-05 US disclosed
EP-2339594-B1 COMPOSITION FOR PRODUCING METAL FILM, METHOD FOR PRODUCING METAL FILM, AND METHOD FOR PRODUCING METAL POWDER TOSOH CORP (JP) 2018-01-03 EP disclosed
US-20060241324-A1 Method for the hydroformylation of olefinically unsaturated compounds, especially olefins,in the presence of cyclic carbonic acid esters OXENO OLEFINCHEMIE GMBH (DE) 2006-10-26 US disclosed
US-20050288257-A1 Novel stable compositions of water and oxygen sensitive compounds and their method of preparation NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2005-12-29 US disclosed
US-20050209489-A1 Method for producing aldehydes by means of hydroformylation of olefinically unsaturated compounds, said hydroformylation being catalyzed by unmodified metal complexes in the presence of cyclic carbonic acid esters OXENO OLEFINCHEMIE GMBH (DE) 2005-09-22 US disclosed
EP-0479541-B1 Iridium-optically active phosphine complex and catalytic production of optically active alcohols therewith TAKASAGO PERFUMERY CO LTD (JP) 1995-07-19 EP disclosed
US-5210332-A Iridium-optically active phosphine complex and process for producing optically active alcohols using the same TAKASAGO INTERNATIONAL CORPORATION (JP) 1993-05-11 US disclosed
US-5159093-A IRIDIUM-OPTICALLY ACTIVE PHOSPHINE COMPLEX AND PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOLS USING THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 1992-10-27 US disclosed
EP-0479541-A1 Iridium-optically active phosphine complex and catalytic production of optically active alcohols therewith Takasago International Corporation (JP) 1992-04-08 EP disclosed
EP-0294000-A2 Novel diaryl phosphides SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110137086-A1 PROCESS FOR TELOMERIZATION OF BUTADIENE HRH3, HRH4, TELO2 APP 4178/4885CA12 4195/4885CA1 4615/4885
US-12617952-B1 Self-ameliorate-fissure-responsive pod system for alkyd-polyester aircraft runway paint PARG, PLOD3, PARN APP 4110/4885CA12 4326/4885CA1 4739/4885
US-20060241324-A1 Method for the hydroformylation of olefinically unsaturated compounds, especially olefins,in the presence of cyclic carbonic acid esters ELOVL6, ELOVL1, ELOVL5 APP 3890/4885CA12 51/4885CA1 54/4885
US-20050288257-A1 Novel stable compositions of water and oxygen sensitive compounds and their method of preparation COXFA4L2, CYP2F1, ABCG2 APP 2546/4885CA12 551/4885CA1 388/4885
US-20050209489-A1 Method for producing aldehydes by means of hydroformylation of olefinically unsaturated compounds, said hydroformylation being catalyzed by unmodified metal complexes in the presence of cyclic carbonic acid esters HACL2, ALDH3A1, ADH4 APP 3126/4885CA12 60/4885CA1 74/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.