SCHEMBL987983

SCHEMBL987983

OCc1cccc(O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2O)c1

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.44
SLC5A2 P31639 10/20 0.42
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA9 Q16790 2/20 0.39
TYR P14679 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5326849 0.87 ACHE (0.43) ACHESLC5A2CA12CA1CA9
SCHEMBL9014071 0.85 CA12 (0.48) SLC5A2CA12CA1CA9TYR
SCHEMBL9014322 0.85 CA12 (0.48) SLC5A2CA12CA1CA9TYR
SCHEMBL9014307 0.85 CA12 (0.48) SLC5A2CA12CA1CA9TYR
SCHEMBL9013970 0.85 CA12 (0.48) SLC5A2CA12CA1CA9TYR
SCHEMBL1076034 0.83 TYR (0.49) ACHESLC5A2TYR
SCHEMBL5728675 0.83 TYR (0.48) SLC5A2TYR
SCHEMBL4651595 0.83 TYR (0.48) SLC5A2TYR
SCHEMBL868745 0.83 TYR (0.48) SLC5A2TYR
SCHEMBL14975449 0.83 TYR (0.48) SLC5A2TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240050458-A1 Compositions And Methods For Inducing Apopotosis In Anaerobic Cells And Related Clinical Methods For Treating Cancer And Pathogenic Infections ROBERTS SUZANNAH JANE (US) 2024-02-15 US disclosed
US-20200360408-A1 Compositions And Methods For Inducing Apoptosis In Anaerobic Cells And Related Clinical Methods For Treating Cancer And Pathogenic Infections COGNATE 3 LLC 2020-11-19 US disclosed
US-20200253998-A1 Compositions And Methods For Immunotherapy BROWN JOE ERNEST (US) 2020-08-13 US disclosed
US-20160113955-A1 Compositions And Methods For Immunotherapy BROWN JOE ERNEST (US) 2016-04-28 US disclosed
US-20160008388-A1 COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY BROWN JOE ERNEST (US) 2016-01-14 US disclosed
US-20120251490-A1 Compositions And Methods For Immunotherapy BROWN JOE ERNEST (US) 2012-10-04 US disclosed
US-20110311478-A1 Combinatorial Methods For Treating Cellular Proliferative Disorders And Immune Deficiencies Using Salicinium BROWN JOE ERNEST (US) 2011-12-22 US disclosed
US-20110311477-A1 Infusion Treatment Methods And Compositions Using Salicinium For Treating Cellular Proliferative Disorders And Immune Deficiencies BROWN JOE ERNEST (US) 2011-12-22 US disclosed
US-20110311476-A1 Methods For Treating An Immune Deficiency Or Enhancing Immune Function Using Salicinium, Non-Limited In Terms Of Treatment Indication, But Encompassing Methods For Treating Cancer And Microbial, Bacterial, Viral, Fungal; Non-Limited In Terms of Delivery Mode, Formulation BROWN JOE ERNEST (US) 2011-12-22 US disclosed
EP-2271350-A1 COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY Cognate3, LLC. (US) 2011-01-12 EP disclosed
WO-2009145841-A1 COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY COGNATE 3, LLC (US) 2009-12-03 WO disclosed
US-20090281047-A1 Compositions And Methods For Immunotherapy COGNATE3 LLC 2009-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160008388-A1 COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY ICOS, IL2, NFATC1 ACHE 1809/4885SLC5A2 3415/4885CA12 451/4885
US-20090281047-A1 Compositions And Methods For Immunotherapy ICOS, IL2, NFATC1 ACHE 1809/4885SLC5A2 3415/4885CA12 451/4885
US-20240050458-A1 Compositions And Methods For Inducing Apopotosis In Anaerobic Cells And Related Clinical Methods For Treating Cancer And Pathogenic Infections ENGASE, AGL, GAA ACHE 495/4885SLC5A2 1011/4885CA12 239/4885
US-20110311478-A1 Combinatorial Methods For Treating Cellular Proliferative Disorders And Immune Deficiencies Using Salicinium NFATC1, MKI67, MYD88 ACHE 3616/4885SLC5A2 3148/4885CA12 1844/4885
US-20110311477-A1 Infusion Treatment Methods And Compositions Using Salicinium For Treating Cellular Proliferative Disorders And Immune Deficiencies IDO1, MKI67, ADSL ACHE 3767/4885SLC5A2 754/4885CA12 1607/4885
US-20110311476-A1 Methods For Treating An Immune Deficiency Or Enhancing Immune Function Using Salicinium, Non-Limited In Terms Of Treatment Indication, But Encompassing Methods For Treating Cancer And Microbial, Bacterial, Viral, Fungal; Non-Limited In Terms of Delivery Mode, Formulation IDO1, TLR5, IDO2 ACHE 3232/4885SLC5A2 1048/4885CA12 1801/4885
US-20120251490-A1 Compositions And Methods For Immunotherapy ICOS, IL2, NFATC1 ACHE 1809/4885SLC5A2 3415/4885CA12 451/4885
US-20200360408-A1 Compositions And Methods For Inducing Apoptosis In Anaerobic Cells And Related Clinical Methods For Treating Cancer And Pathogenic Infections ENGASE, AGL, GAA ACHE 786/4885SLC5A2 1160/4885CA12 228/4885
US-20200253998-A1 Compositions And Methods For Immunotherapy ICOS, NFATC1, IL2 ACHE 1768/4885SLC5A2 3588/4885CA12 678/4885
US-20160113955-A1 Compositions And Methods For Immunotherapy ICOS, IL2, NFATC1 ACHE 1809/4885SLC5A2 3415/4885CA12 451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.