Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615816 | 0.78 | ALDH1A1 (0.34) | ALDH1A1TSHRHTT | |
| SCHEMBL1245995 | 0.76 | ALDH1A1 (0.33) | ALDH1A1TSHRHTT | |
| SCHEMBL873725 | 0.74 | TSHR (0.45) | ALDH1A1TSHRHTT | |
| SCHEMBL1114546 | 0.74 | — | — | |
| SCHEMBL7371095 | 0.74 | — | — | |
| SCHEMBL8613379 | 0.74 | ALDH1A1 (0.32) | ALDH1A1TSHRHTT | |
| SCHEMBL6831466 | 0.72 | ALDH1A1 (0.38) | ALDH1A1TSHRHTT | |
| SCHEMBL17818667 | 0.72 | ALDH1A1 (0.43) | ALDH1A1TSHRHTT | |
| SCHEMBL5615548 | 0.72 | ALDH1A1 (0.34) | ALDH1A1TSHRHTT | |
| SCHEMBL1640508 | 0.72 | HTT (0.45) | ALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999366-A | Treatment of hyperlipidemia | THE NORTH CAROLINA CENTRAL UNIV. (US) | 1991-03-12 | — | — | US | disclosed |
| US-4946963-A | HYPOLIPIDEMIC AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1990-08-07 | — | — | US | disclosed |
| EP-0321090-A2 | Isoxazolidine-3,5-diones in the treatment of hyperlipidemia | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1989-06-21 | — | — | EP | disclosed |