SCHEMBL1245995

SCHEMBL1245995

C=CCC(O)(CC=C)C(=O)Cl

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8615816 0.76 ALDH1A1 (0.34) ALDH1A1TSHRHTT
SCHEMBL9879834 0.76 ALDH1A1 (0.34) ALDH1A1TSHRHTT
SCHEMBL770454 0.76 ALDH1A1 (0.43) ALDH1A1TSHRHTT
SCHEMBL7591068 0.74 ALDH1A1 (0.33) ALDH1A1TSHRHTT
SCHEMBL7899169 0.74 HTT (0.44) ALDH1A1TSHRHTT
SCHEMBL1114546 0.72
SCHEMBL8613379 0.72 ALDH1A1 (0.32) ALDH1A1TSHRHTT
SCHEMBL7371095 0.72
SCHEMBL7923091 0.72 CA4 (0.48) ALDH1A1TSHRHTT
SCHEMBL10604493 0.70 ALDH1A1 (0.35) ALDH1A1TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2394676-B1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITIATOR-CONTAINING SCAFFOLDS COLOPLAST AS (DK) 2018-03-28 EP disclosed
EP-2459242-B1 A MEDICAL DEVICE OF POLYOLEFIN COLOPLAST AS (DK) 2015-10-21 EP disclosed
EP-2104523-B1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST AS (DK) 2015-08-26 EP disclosed
US-8932662-B2 Coatings prepared from poly(ethylene oxide) and photo-initator-containing scaffolds COLOPLAST A/S (DK) 2015-01-13 US disclosed
EP-2459242-A2 A MEDICAL DEVICE OF POLYOLEFIN Coloplast A/S (DK) 2012-06-06 EP disclosed
US-20120121919-A1 MEDICAL DEVICE OF POLYOLEFIN COLOPLAST A/S (DK) 2012-05-17 US disclosed
WO-2011012137-A2 A MEDICAL DEVICE OF POLYOLEFIN COLOPLAST A/S (DK) 2011-02-03 WO disclosed
US-20100049146-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST A/S (DK) 2010-02-25 US disclosed