Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84280 | 0.81 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AKDM4EMAPK1 | |
| SCHEMBL325229 | 0.80 | KMT2A (0.38) | ALDH1A1RECQLTAAR1MEN1KMT2A | |
| SCHEMBL8544254 | 0.79 | — | — | |
| Fluoride SCHEMBL28515671 | 0.79 | ALDH1A1 (0.40) | ALDH1A1NPC1RAB9AKDM4EMAPK1 | |
| SCHEMBL29175978 | 0.77 | — | — | |
| SCHEMBL11022719 | 0.77 | — | — | |
| SCHEMBL9564409 | 0.77 | USP2 (0.31) | NPC1RAB9AKDM4EMAPK1USP2 | |
| SCHEMBL7958544 | 0.76 | ADRA2A (0.32) | ALDH1A1NPC1RAB9ATAAR1FBP1 | |
| SCHEMBL5792903 | 0.74 | ALDH1A1 (0.35) | ALDH1A1NPC1RAB9AKDM4EMAPK1 | |
| SCHEMBL27459264 | 0.74 | ALDH1A1 (0.37) | ALDH1A1NPC1RAB9AKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274324-B1 | PROCESS FOR THE PREPARATION OF THIENYLETHYL AMINES, AND DITHIENYLETHYL AMINES SO OBTAINED | SANOFI (FR) | 1991-02-06 | — | — | EP | disclosed |
| EP-0274324-A1 | Process for the preparation of thienylethyl amines, and dithienylethyl amines so obtained | SANOFI (FR) | 1988-07-13 | — | — | EP | disclosed |