Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.57 |
| ▸ | TNIK | Q9UKE5 | 9/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.44 |
| ▸ | CBFB | Q13951 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9878706 | 0.83 | KMT2A (0.50) | GAAMAPTALDH1A1LMNAAGPAT2 | |
| SCHEMBL7644039 | 0.68 | GAA (0.61) | GAATNIKMAPTKDM4EALDH1A1 | |
| SCHEMBL10863598 | 0.68 | NOS2 (0.57) | KDM4EALDH1A1LMNAKMT2ANOS3 | |
| SCHEMBL30227466 | 0.67 | NOS2 (0.48) | GAAMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL13153625 | 0.67 | NOS2 (0.48) | GAAMAPTKDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9879424 | 0.67 | KMT2A (0.50) | GAAMAPTLMNAMEN1KMT2A | |
| SCHEMBL2408632 | 0.66 | NUDT1 (0.52) | GAAMAPTLMNAKMT2AHPGD | |
| SCHEMBL30991860 | 0.65 | CYP3A4 (0.71) | GAATNIKMAPTKDM4EALDH1A1 | |
| SCHEMBL20612556 | 0.65 | CYP3A4 (0.71) | GAATNIKMAPTKDM4EALDH1A1 | |
| SCHEMBL8364061 | 0.65 | NOS2 (0.55) | GAANOS3NOS1NOS2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018887-A1 | DIAMINOPYRIMIDINE COMPOUNDS | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1991-12-12 | — | — | WO | disclosed |