Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310001 | 0.86 | NPC1 (0.56) | NPC1RAB9ALMNAHSD17B10MAPT | |
| SCHEMBL1515794 | 0.84 | MAPT (0.59) | NPC1RAB9ALMNAHSD17B10MAPT | |
| SCHEMBL9879912 | 0.83 | NPC1 (0.56) | NPC1RAB9ALMNAHSD17B10MAPT | |
| SCHEMBL9879844 | 0.83 | ALDH1A1 (0.43) | NPC1RAB9ALMNAHSD17B10MAPT | |
| SCHEMBL9650486 | 0.82 | NPC1 (0.67) | NPC1RAB9ALMNAHSD17B10MAPT | |
| SCHEMBL9879580 | 0.82 | FFAR1 (0.48) | NPC1RAB9AMAPTSMN1; SMN2POLB | |
| SCHEMBL5204910 | 0.81 | MAPT (0.56) | NPC1RAB9ALMNAHSD17B10MAPT | |
| SCHEMBL8946781 | 0.79 | NPC1 (0.63) | NPC1RAB9ALMNAHSD17B10MAPT | |
| SCHEMBL10582715 | 0.79 | MAPT (0.43) | NPC1RAB9ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL9284657 | 0.78 | MAPT (0.48) | NPC1RAB9ALMNAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5053507-A | Liquid crystal dopants | ARAKAWA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-10-01 | — | — | US | disclosed |