Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | FOS | P01100 | 3/20 | 0.45 |
| ▸ | JUN | P05412 | 3/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11813302 | 0.87 | NPC1 (0.62) | NPC1RAB9ALMNAHSD17B10ALDH1A1 | |
| SCHEMBL11786860 | 0.87 | NPC1 (0.69) | NPC1RAB9ALMNAHSD17B10ALDH1A1 | |
| SCHEMBL11780312 | 0.86 | NPC1 (0.71) | NPC1RAB9ALMNAHSD17B10ALDH1A1 | |
| SCHEMBL9879862 | 0.85 | ALDH1A1 (0.52) | NPC1RAB9ALMNAHSD17B10ALDH1A1 | |
| SCHEMBL11610894 | 0.85 | NPC1 (0.77) | NPC1RAB9ALMNAHSD17B10ALDH1A1 | |
| SCHEMBL9879895 | 0.83 | NPC1 (0.48) | NPC1RAB9ALMNAHSD17B10ALDH1A1 | |
| SCHEMBL11785304 | 0.83 | ALDH1A1 (0.60) | NPC1RAB9ALMNAHSD17B10ALDH1A1 | |
| SCHEMBL8946955 | 0.82 | NPC1 (0.72) | NPC1RAB9ALMNAHSD17B10ALDH1A1 | |
| SCHEMBL10823986 | 0.81 | ALDH1A1 (0.59) | NPC1RAB9ALMNAHSD17B10ALDH1A1 | |
| SCHEMBL4849077 | 0.80 | ALDH1A1 (0.76) | NPC1RAB9ALMNAHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5053507-A | Liquid crystal dopants | ARAKAWA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-10-01 | — | — | US | disclosed |