Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 3/20 | 0.48 |
| ▸ | NOS3 | P29474 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | TAS2R38 | P59533 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18774078 | 1.00 | GAA (0.51) | GAAKMT2AMEN1RAB9AMAPT | |
| SCHEMBL3086579 | 0.81 | GAA (0.50) | GAAKMT2AMEN1RAB9AMAPT | |
| SCHEMBL2746282 | 0.81 | GAA (0.53) | GAAKMT2AMEN1RAB9AMAPT | |
| SCHEMBL8476490 | 0.79 | GAA (0.66) | GAAKMT2AMEN1RAB9AMAPT | |
| SCHEMBL8476492 | 0.79 | GFER (0.57) | GAAKMT2AMEN1RAB9AMAPT | |
| SCHEMBL11674433 | 0.77 | GAA (0.47) | GAAKMT2AMEN1RAB9AMAPT | |
| SCHEMBL17119830 | 0.77 | GAA (0.47) | GAAKMT2AMEN1RAB9AMAPT | |
| SCHEMBL26537590 | 0.77 | GAA (0.47) | GAAKMT2AMEN1RAB9AMAPT | |
| SCHEMBL7487475 | 0.77 | MAPT (0.51) | GAAKMT2AMEN1RAB9AMAPT | |
| SCHEMBL7487469 | 0.77 | MAPT (0.51) | GAAKMT2AMEN1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188128-B2 | Opioid receptor subtype-selective agents | THE UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2012-05-29 | — | — | US | disclosed |
| US-20090181998-A1 | OPIOID RECEPTOR SUBTYPE-SELECTIVE AGENTS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181998-A1 | OPIOID RECEPTOR SUBTYPE-SELECTIVE AGENTS | OPRM1, OPRK1, OPRL1 | GAA 2229/4885KMT2A 3374/4885MEN1 4845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.