⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6761845 | 0.78 | TRPA1 (0.37) | — | |
| SCHEMBL13991691 | 0.78 | LCK (0.37) | — | |
| SCHEMBL26520993 | 0.77 | — | — | |
| SCHEMBL26450921 | 0.75 | — | — | |
| SCHEMBL539353 | 0.75 | — | — | |
| SCHEMBL23775550 | 0.75 | — | — | |
| SCHEMBL19628871 | 0.75 | — | — | |
| SCHEMBL28016360 | 0.75 | ALDH1A1 (0.42) | — | |
| SCHEMBL27473475 | 0.73 | ALDH1A1 (0.61) | — | |
| SCHEMBL5149182 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10611746-B2 | Method for producing 2-acetyl-4H,9H-naphtho[2,3-B]furan-4,9-dione | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-04-07 | — | — | US | claimed |
| US-20190263769-A1 | METHOD FOR PRODUCING 2-ACETYL-4H,9H-NAPHTHO[2,3-B]FURAN-4,9-DIONE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2019-08-29 | — | — | US | claimed |
| US-10329267-B2 | Method for producing 2-acetyl-4H,9H-naphtho[2,3-b]furan-4,9-dione | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2019-06-25 | — | — | US | claimed |
| US-20180201597-A1 | METHOD FOR PRODUCING 2-ACETYL-4H,9H-NAPHTHO[2,3-B]FURAN-4,9-DIONE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2018-07-19 | — | — | US | claimed |
| EP-2547334-B1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TARGETING CANCER STEM CELLS | 1GLOBE BIOMEDICAL CO LTD (CN) | 2017-11-15 | — | — | EP | claimed |
| US-20130034591-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TARGETING CANCER STEM CELLS | BOSTON BIOMEDICAL, INC. (US) | 2013-02-07 | — | — | US | claimed |
| EP-2547334-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TARGETING CANCER STEM CELLS | Boston Biomedical, Inc. (US) | 2013-01-23 | — | — | EP | claimed |
| WO-2011116398-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TARGETING CANCER STEM CELLS | BOSTON BIOMEDICAL, INC. (US) | 2011-09-22 | — | — | WO | claimed |
| EP-2547205-B1 | NOVEL METHODS FOR TARGETING CANCER STEM CELLS | 1GLOBE BIOMEDICAL CO LTD (CN) | 2024-03-20 | — | — | EP | disclosed |
| CN-107375260-B | Novel compounds and compositions for targeting cancer stem cells | 北京强新生物科技有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-115475253-B | Lapatinib-cancer cell stem inhibitor conjugate, preparation method, pharmaceutical composition and application | 东南大学 | 2023-09-29 | — | — | CN | disclosed |
| US-11739074-B2 | Ras inhibitors | Revolution Medicines, Inc. (US) | 2023-08-29 | — | — | US | disclosed |
| US-20230233569-A1 | METHODS FOR DELAYING, PREVENTING, AND TREATING ACQUIRED RESISTANCE TO RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-07-27 | — | — | US | disclosed |
| CN-115475253-A | Lapatinib-cancer cell dryness inhibitor conjugate, preparation method, pharmaceutical composition and application | 东南大学 | 2022-12-16 | — | — | CN | disclosed |
| US-4087488-A | Cyano-4-(0,0-dialkylphosphoryloxy)-cyclohex-4-enes | HOFFMAN-LA ROCHE INC. (US) | 1978-05-02 | — | — | US | disclosed |
| US-4077985-A | 4-(O,O-Diester phosphoryloxy)cyclohex-4-en-1,2-carboxylic anhydrides | HOFFMANN-LA ROCHE INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4025584-A | 1-Acetyl-3(4)-(dihydrocarbylphosphoryloxy)-cyclohex-3-enes | HOFFMANN-LA ROCHE INC. (US) | 1977-05-24 | — | — | US | disclosed |
| US-3978171-A | PROCESS FOR THE PREPARATION OF DIENYLPHOSPHATES | HOFFMANN-LA ROCHE INC. (US) | 1976-08-31 | — | — | US | disclosed |
| US-3978172-A | PROCESS FOR THE PREPARATION OF DIENYLPHOSPHATES | HOFFMANN-LA ROCHE INC. (US) | 1976-08-31 | — | — | US | disclosed |
| US-3933948-A | Dienylphosphates | HOFFMANN-LA ROCHE INC. (US) | 1976-01-20 | — | — | US | disclosed |