Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 5/20 | 0.82 |
| ▸ | CTSS | P25774 | 2/20 | 0.82 |
| ▸ | CTSH | P09668 | 2/20 | 0.82 |
| ▸ | CTSK | P43235 | 2/20 | 0.82 |
| ▸ | CTSC | P53634 | 2/20 | 0.82 |
| ▸ | CTSL | P07711 | 6/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359034 | 1.00 | CTSB (0.82) | CTSBCTSSCTSHCTSKCTSC | |
| SCHEMBL4447645 | 0.90 | CTSB (0.80) | CTSBCTSSCTSHCTSKCTSC | |
| SCHEMBL4994654 | 0.89 | CTSB (0.79) | CTSBCTSSCTSHCTSKCTSC | |
| SCHEMBL7856906 | 0.88 | CTSB (0.78) | CTSBCTSSCTSHCTSKCTSC | |
| SCHEMBL9891652 | 0.85 | CTSL (0.73) | CTSBCTSSCTSHCTSKCTSC | |
| SCHEMBL5417089 | 0.83 | CTSB (0.64) | CTSBCTSSCTSHCTSKCTSC | |
| SCHEMBL5417093 | 0.83 | CTSB (0.64) | CTSBCTSSCTSHCTSKCTSC | |
| SCHEMBL7349455 | 0.81 | CTSB (0.56) | CTSBCTSSCTSHCTSKCTSC | |
| SCHEMBL7355598 | 0.81 | CTSB (0.56) | CTSBCTSSCTSHCTSKCTSC | |
| SCHEMBL7361801 | 0.81 | CTSL (0.67) | CTSBCTSSCTSHCTSKCTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150369816-A1 | Polypeptide Immobilization | UNIV CHICAGO (US) | 2015-12-24 | — | — | US | disclosed |
| US-20150369816-A1 | Polypeptide Immobilization | UNIV CHICAGO (US) | 2015-12-24 | — | — | US | disclosed |
| US-9074300-B2 | Polypeptide immobilization | THE UNIVERSITY OF CHICAGO (US) | 2015-07-07 | — | — | US | disclosed |
| EP-1552305-B1 | POLYPEPTIDE IMMOBILIZATION | UNIV CHICAGO (US) | 2013-07-31 | — | — | EP | disclosed |
| US-20120142547-A1 | POLYPEPTIDE IMMOBILIZATION | THE UNIVERSITY OF CHICAGO | 2012-06-07 | — | — | US | disclosed |
| US-20120142547-A1 | POLYPEPTIDE IMMOBILIZATION | THE UNIVERSITY OF CHICAGO | 2012-06-07 | — | — | US | disclosed |
| EP-2311939-A1 | Polypeptide immobilization | The University of Chicago (US) | 2011-04-20 | — | — | EP | disclosed |
| US-7888055-B2 | Selectively binds with absolute control over orientation and density without requiring prior synthetic modification or purification to make a stable protein chip; rapid and irreversible; assaying kinase or protease activity | THE UNIVERSITY OF CHICAGO (US) | 2011-02-15 | — | — | US | disclosed |
| US-7888055-B2 | Selectively binds with absolute control over orientation and density without requiring prior synthetic modification or purification to make a stable protein chip; rapid and irreversible; assaying kinase or protease activity | THE UNIVERSITY OF CHICAGO (US) | 2011-02-15 | — | — | US | disclosed |
| US-20080064606-A1 | Polypeptide immobilization | THE UNIVERSITY OF CHICAGO | 2008-03-13 | — | — | US | disclosed |
| US-20080064606-A1 | Polypeptide immobilization | THE UNIVERSITY OF CHICAGO | 2008-03-13 | — | — | US | disclosed |
| US-7172905-B2 | Polypeptide immobilization | THE UNIVERSITY OF CHICAGO (US) | 2007-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064606-A1 | Polypeptide immobilization | QPCTL, SURF4, QPCT | CTSB 1294/4885CTSS 2186/4885CTSH 1512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.