Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 11/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 11/20 | 0.47 |
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052031 | 0.80 | GABRA1 (0.46) | GABRA1GABRB2CNR2ALOX5CNR1 | |
| SCHEMBL9889146 | 0.77 | CCR5 (0.41) | GABRA1GABRB2CNR2MEN1GAA | |
| SCHEMBL821126 | 0.75 | GABRA1 (0.72) | GABRA1GABRB2CNR2ALOX5CNR1 | |
| SCHEMBL5882568 | 0.74 | GABRA1 (0.61) | GABRA1GABRB2CNR2ALOX5CNR1 | |
| SCHEMBL9436388 | 0.74 | GABRA1 (0.61) | GABRA1GABRB2CNR2ALOX5CNR1 | |
| SCHEMBL240238 | 0.73 | GABRA1 (0.66) | GABRA1GABRB2CNR2ALOX5CNR1 | |
| SCHEMBL29463215 | 0.73 | GABRA1 (0.66) | GABRA1GABRB2CNR2ALOX5CNR1 | |
| SCHEMBL20840187 | 0.73 | GABRA1 (0.66) | GABRA1GABRB2CNR2ALOX5CNR1 | |
| SCHEMBL8419816 | 0.73 | GABRA1 (0.49) | GABRA1GABRB2CNR2ALOX5CNR1 | |
| SCHEMBL8417679 | 0.73 | GABRA1 (0.46) | GABRA1GABRB2CNR2ALOX5CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150369816-A1 | Polypeptide Immobilization | UNIV CHICAGO (US) | 2015-12-24 | — | — | US | disclosed |
| US-9074300-B2 | Polypeptide immobilization | THE UNIVERSITY OF CHICAGO (US) | 2015-07-07 | — | — | US | disclosed |
| US-20120142547-A1 | POLYPEPTIDE IMMOBILIZATION | THE UNIVERSITY OF CHICAGO | 2012-06-07 | — | — | US | disclosed |
| US-7888055-B2 | Selectively binds with absolute control over orientation and density without requiring prior synthetic modification or purification to make a stable protein chip; rapid and irreversible; assaying kinase or protease activity | THE UNIVERSITY OF CHICAGO (US) | 2011-02-15 | — | — | US | disclosed |
| US-20080064606-A1 | Polypeptide immobilization | THE UNIVERSITY OF CHICAGO | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064606-A1 | Polypeptide immobilization | QPCTL, SURF4, QPCT | GABRA1 1489/4885GABRB2 1666/4885CNR2 4750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.