Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.38 |
| ▸ | INPPL1 | O15357 | 5/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.38 |
| ▸ | INPP5A | Q14642 | 3/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | INPP5B | P32019 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17358703 | 0.85 | PPARA (0.42) | PPARDPPARAFFAR1FFAR4PTGER1 | |
| SCHEMBL13182856 | 0.76 | KDM4E (0.53) | FFAR1INPPL1INPP5APTGER1PTGER4 | |
| SCHEMBL30414237 | 0.75 | GAA (0.45) | FFAR1INPPL1FFAR4INPP5AAKT1 | |
| SCHEMBL17027965 | 0.74 | BACE1 (0.43) | INPPL1INPP5AAKT1INPP5B | |
| SCHEMBL9889198 | 0.73 | SELP (0.36) | PPARDPPARAFFAR1FFAR4 | |
| SCHEMBL1979080 | 0.72 | NR1I2 (0.47) | — | |
| SCHEMBL9889095 | 0.70 | MTNR1A (0.40) | PPARDPPARA | |
| SCHEMBL30153849 | 0.70 | FFAR1 (0.41) | FFAR1FFAR4 | |
| SCHEMBL6480565 | 0.70 | INPPL1 (0.44) | PPARAINPPL1INPP5AAKT1INPP5B | |
| SCHEMBL8819841 | 0.70 | PPARA (0.58) | PPARDPPARAFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9074300-B2 | Polypeptide immobilization | THE UNIVERSITY OF CHICAGO (US) | 2015-07-07 | — | — | US | disclosed |
| US-9074300-B2 | Polypeptide immobilization | THE UNIVERSITY OF CHICAGO (US) | 2015-07-07 | — | — | US | disclosed |
| US-20120142547-A1 | POLYPEPTIDE IMMOBILIZATION | THE UNIVERSITY OF CHICAGO | 2012-06-07 | — | — | US | disclosed |
| US-20120142547-A1 | POLYPEPTIDE IMMOBILIZATION | THE UNIVERSITY OF CHICAGO | 2012-06-07 | — | — | US | disclosed |
| US-7888055-B2 | Selectively binds with absolute control over orientation and density without requiring prior synthetic modification or purification to make a stable protein chip; rapid and irreversible; assaying kinase or protease activity | THE UNIVERSITY OF CHICAGO (US) | 2011-02-15 | — | — | US | disclosed |
| US-7888055-B2 | Selectively binds with absolute control over orientation and density without requiring prior synthetic modification or purification to make a stable protein chip; rapid and irreversible; assaying kinase or protease activity | THE UNIVERSITY OF CHICAGO (US) | 2011-02-15 | — | — | US | disclosed |
| US-20080064606-A1 | Polypeptide immobilization | THE UNIVERSITY OF CHICAGO | 2008-03-13 | — | — | US | disclosed |
| US-20080064606-A1 | Polypeptide immobilization | THE UNIVERSITY OF CHICAGO | 2008-03-13 | — | — | US | disclosed |
| US-7172905-B2 | Polypeptide immobilization | THE UNIVERSITY OF CHICAGO (US) | 2007-02-06 | — | — | US | disclosed |
| US-7172905-B2 | Polypeptide immobilization | THE UNIVERSITY OF CHICAGO (US) | 2007-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064606-A1 | Polypeptide immobilization | QPCTL, SURF4, QPCT | PPARD 1506/4885PPARA 997/4885FFAR1 891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.