SCHEMBL9890144

SCHEMBL9890144

c1ccc2c(c1)c1ccccc1n2-c1ccc2oc3c(ccc4c5cc(-n6c7ccccc7c7ccccc76)ccc5oc43)c2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALDH1A1 P00352 6/20 0.36
KMT2A Q03164 3/20 0.36
NPC1 O15118 3/20 0.36
MEN1 O00255 2/20 0.36
MAPT P10636 2/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
HPGD P15428 1/20 0.36
PPARG P37231 5/20 0.36
RXFP1 Q9HBX9 5/20 0.36
NR2E3 Q9Y5X4 5/20 0.36
NCOR2 Q9Y618 5/20 0.36
NPSR1 Q6W5P4 3/20 0.36
LMNA P02545 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
AHR P35869 2/20 0.36
DYRK1A Q13627 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9890183 0.94 KDM4E (0.41) KDM4EATML3MBTL1ALDH1A1KMT2A
SCHEMBL9890185 0.93 KDM4E (0.40) KDM4EATML3MBTL1ALDH1A1KMT2A
SCHEMBL9890189 0.91 KDM4E (0.39) KDM4EATML3MBTL1ALDH1A1KMT2A
SCHEMBL9890142 0.91 ALDH1A1 (0.40) KDM4EATML3MBTL1ALDH1A1KMT2A
SCHEMBL14039031 0.91 KDM4E (0.39) KDM4EATML3MBTL1ALDH1A1NPC1
SCHEMBL9890384 0.91 KDM4E (0.41) KDM4EATML3MBTL1ALDH1A1KMT2A
SCHEMBL9890139 0.90 KDM4E (0.38) KDM4EATML3MBTL1ALDH1A1KMT2A
SCHEMBL9890141 0.90 KDM4E (0.41) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL9890140 0.90 KDM4E (0.41) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL9890145 0.90 KDM4E (0.40) KDM4EATML3MBTL1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9647220-B2 Organic multicolor light-emitting apparatus SONY CORPORATION (JP) 2017-05-09 US disclosed
US-9647220-B2 Organic multicolor light-emitting apparatus SONY CORPORATION (JP) 2017-05-09 US disclosed
US-20160276602-A1 ORGANIC MULTICOLOR LIGHT-EMITTING APPARATUS SONY CORPORATION (JP) 2016-09-22 US disclosed
US-20160276602-A1 ORGANIC MULTICOLOR LIGHT-EMITTING APPARATUS SONY CORPORATION (JP) 2016-09-22 US disclosed
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-01-24 US disclosed
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-01-24 US disclosed
US-8318323-B2 Polycyclic compounds and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2012-11-27 US disclosed
US-8318323-B2 Polycyclic compounds and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2012-11-27 US disclosed
US-20120138915-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed
US-20120138915-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed
US-20100012931-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME KCNC1, EED, BMI1 KDM4E 990/4885ATM 3103/4885L3MBTL1 709/4885
US-20100012931-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME KCNC1, EED, BMI1 KDM4E 990/4885ATM 3103/4885L3MBTL1 709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.