SCHEMBL9890160

SCHEMBL9890160

c1ccc(-c2cccc(-c3ccc4oc5c(ccc6c7cc(-n8c9ccccc9c9ccccc98)ccc7oc65)c4c3)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 4/20 0.40
PLA2G4A P47712 4/20 0.40
PLA2G10 O15496 1/20 0.40
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PRKDC P78527 3/20 0.39
PGR P06401 1/20 0.35
HDAC4 P56524 1/20 0.34
PTPRF P10586 6/20 0.34
PTPN2 P17706 6/20 0.34
PTPN1 P18031 6/20 0.34
ALOX5 P09917 1/20 0.34
PIM1 P11309 1/20 0.33
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
PIM3 Q86V86 1/20 0.33
PIM2 Q9P1W9 1/20 0.33
EDNRB P24530 1/20 0.33
EDNRA P25101 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9890161 0.97 PLA2G2A (0.39) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL9890141 0.97 KDM4E (0.41) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL9890140 0.97 KDM4E (0.41) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL9890186 0.97 PLA2G2A (0.39) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL9890164 0.96 PLA2G2A (0.40) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL9890185 0.95 KDM4E (0.40) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL9890146 0.94 PLA2G2A (0.40) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL9890155 0.94 KDM4E (0.40) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL9890189 0.93 KDM4E (0.39) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL9890183 0.93 KDM4E (0.41) PLA2G2APLA2G4APLA2G10KDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-01-24 US disclosed
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-01-24 US disclosed
US-8318323-B2 Polycyclic compounds and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2012-11-27 US disclosed
US-20120138915-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed
US-20120138915-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed
EP-2301921-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2011-03-30 EP disclosed
US-20100012931-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME KCNC1, EED, BMI1 PLA2G2A 4239/4885PLA2G4A 4728/4885PLA2G10 4642/4885
US-20100012931-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME KCNC1, EED, BMI1 PLA2G2A 4239/4885PLA2G4A 4728/4885PLA2G10 4642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.