SCHEMBL9890198

SCHEMBL9890198

c1cc2c(cn1)c1cnccc1n2-c1ccc2oc3c(ccc4c5cc(-n6c7ccncc7c7cnccc76)ccc5oc43)c2c1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.33
MAOA P21397 4/20 0.31
MAOB P27338 4/20 0.31
ACHE P22303 1/20 0.31
USP14 P54578 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9890194 0.95 CDK4 (0.33) AHRMAOAMAOBACHE
SCHEMBL13529136 0.95 CDK4 (0.33) AHRMAOAMAOBACHE
SCHEMBL9890191 0.93 MAOA (0.42) MAOAMAOBACHE
SCHEMBL9890455 0.92 AHR (0.30) AHR
SCHEMBL12114579 0.91 MAOA (0.34) MAOAMAOBACHEUSP14
SCHEMBL9890193 0.88 CDK4 (0.33) AHR
SCHEMBL13529129 0.88 MAOA (0.33) AHRMAOAMAOBACHEUSP14
SCHEMBL9890454 0.87 CDK4 (0.31)
SCHEMBL9890197 0.87 DDB1 (0.36) MAOAMAOBACHE
SCHEMBL9890199 0.87 NCOA1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-01-24 US disclosed
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-01-24 US disclosed
US-20120138915-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed
US-20120138915-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME KCNC1, EED, BMI1 AHR 1447/4885MAOA 455/4885MAOB 771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.