Sugi Predict

Sugi Predict / Compounds / SCHEMBL9890304

SCHEMBL9890304

SCHEMBL9890304

c1cc(-c2cccc3c2oc2cc4c(cc23)oc2c(-n3c5ccccc5c5ccccc53)cccc24)cc(-c2cccc3c2oc2cc4c(cc23)oc2c(-n3c5ccccc5c5ccccc53)cccc24)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.44
▸ GGPS1 O95749 1/20 0.40
▸ PRKDC P78527 10/20 0.40
▸ PTGES2 Q9H7Z7 1/20 0.35
▸ ALDH1A1 P00352 4/20 0.34
▸ PIK3CD O00329 2/20 0.33
▸ PIK3CA P42336 2/20 0.33
▸ PIK3CB P42338 2/20 0.33
▸ PIK3CG P48736 2/20 0.33
▸ KDM4E B2RXH2 2/20 0.33
▸ BRD4 O60885 2/20 0.33
▸ BRD2 P25440 2/20 0.33
▸ BRD3 Q15059 2/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ PRMT5 O14744 1/20 0.33
▸ WDR77 Q9BQA1 1/20 0.33
▸ PDE2A O00408 1/20 0.33
▸ PIK3C2A O00443 1/20 0.33
▸ PIK3R2 O00459 1/20 0.33
▸ PIK3C2B O00750 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9890269 0.96 PRKDC (0.41) ALOX5GGPS1PRKDCPTGES2ALDH1A1
SCHEMBL9890305 0.96 ALOX5 (0.42) ALOX5GGPS1PRKDCPTGES2ALDH1A1
SCHEMBL9890267 0.95 ALOX5 (0.41) ALOX5GGPS1PRKDCALDH1A1PIK3CD
SCHEMBL9890274 0.94 ALOX5 (0.39) ALOX5GGPS1PRKDCPTGES2ALDH1A1
SCHEMBL9890303 0.93 ALOX5 (0.45) ALOX5GGPS1PRKDCPTGES2ALDH1A1
SCHEMBL9890261 0.92 ALOX5 (0.40) ALOX5GGPS1PRKDCPTGES2ALDH1A1
SCHEMBL9890270 0.92 ALOX5 (0.42) ALOX5GGPS1PRKDCALDH1A1PIK3CD
SCHEMBL9890302 0.92 ALOX5 (0.42) ALOX5GGPS1PRKDCALDH1A1PIK3CD
SCHEMBL5028226 0.92 ALOX5 (0.41) ALOX5GGPS1PRKDCALDH1A1PIK3CD
SCHEMBL9890277 0.91 ALOX5 (0.43) ALOX5GGPS1PRKDCPTGES2PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-01-24 — — US disclosed
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-01-24 — — US disclosed
US-8318323-B2 Polycyclic compounds and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2012-11-27 — — US disclosed
US-8318323-B2 Polycyclic compounds and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2012-11-27 — — US disclosed
US-20120138915-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 — — US disclosed
US-20120138915-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME KCNC1, EED, BMI1 ALOX5 2756/4885GGPS1 1114/4885PRKDC 2162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.