SCHEMBL9890540

SCHEMBL9890540

c1ccc(-c2ccc3c(c2)c2cc(-c4ccc5oc6ccc7oc8ccc(-n9c%10ccccc%10c%10ccccc%109)cc8c7c6c5c4)ccc2n3-c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ATM Q13315 1/20 0.46
PLA2G2A P14555 3/20 0.39
PLA2G4A P47712 3/20 0.39
TSPO P30536 1/20 0.37
HDAC4 P56524 1/20 0.37
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
ALDH1A1 P00352 2/20 0.36
POLB P06746 1/20 0.36
TSHR P16473 1/20 0.36
BRCA1 P38398 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PLA2G10 O15496 1/20 0.35
PRKDC P78527 3/20 0.35
EDNRB P24530 1/20 0.35
EDNRA P25101 1/20 0.35
PGR P06401 1/20 0.35
IL1R1 P14778 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9890537 0.97 L3MBTL1 (0.49) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL9889808 0.96 L3MBTL1 (0.50) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL18266067 0.95 L3MBTL1 (0.49) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL18266013 0.95 L3MBTL1 (0.49) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL22461714 0.95 L3MBTL1 (0.49) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL10331648 0.95 L3MBTL1 (0.49) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL15625340 0.95 L3MBTL1 (0.49) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL14849213 0.95 L3MBTL1 (0.49) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL9890564 0.95 KDM4E (0.43) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL9890531 0.95 KDM4E (0.43) L3MBTL1KDM4EATMPLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-01-24 US disclosed
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-01-24 US disclosed
US-8318323-B2 Polycyclic compounds and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2012-11-27 US disclosed
US-8318323-B2 Polycyclic compounds and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2012-11-27 US disclosed
US-20120138915-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed
US-20120138915-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed
US-20100012931-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130020563-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME KCNC1, EED, BMI1 L3MBTL1 709/4885KDM4E 990/4885ATM 3103/4885
US-20100012931-A1 POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME KCNC1, EED, BMI1 L3MBTL1 709/4885KDM4E 990/4885ATM 3103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.