Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 4/20 | 0.57 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.57 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.57 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.57 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2391274 | 0.86 | PTGER1 (0.44) | PTGER1PTGER4PTGER3PTGER2ENPP2 | |
| SCHEMBL7254493 | 0.84 | PTGER4 (0.75) | PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL538512 | 0.82 | KMT2A (0.60) | PTGER1PTGER4PTGER3PTGER2ENPP2 | |
| SCHEMBL9890735 | 0.82 | CHRM1 (0.44) | PTGER1PTGER4PTGER3PTGER2ENPP2 | |
| SCHEMBL2391613 | 0.81 | FFAR1 (0.53) | PTGER1PTGER4PTGER3PTGER2ENPP2 | |
| SCHEMBL29512995 | 0.81 | KMT2A (0.58) | PTGER1PTGER4PTGER3PTGER2ENPP2 | |
| SCHEMBL27701716 | 0.81 | KMT2A (0.58) | PTGER1PTGER4PTGER3PTGER2ENPP2 | |
| SCHEMBL28594606 | 0.81 | KMT2A (0.58) | PTGER1PTGER4PTGER3PTGER2ENPP2 | |
| Hydrochloric Acid SCHEMBL11895689 | 0.81 | KMT2A (0.58) | PTGER1PTGER4PTGER3PTGER2ENPP2 | |
| Ammonia Solution, Strong SCHEMBL27926479 | 0.81 | KMT2A (0.58) | PTGER1PTGER4PTGER3PTGER2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142771-A1 | BIPHENYLACETAMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-06-07 | — | — | US | disclosed |
| US-20120142771-A1 | BIPHENYLACETAMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-06-07 | — | — | US | disclosed |
| EP-2374790-A1 | BIPHENYLACETAMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2011-10-12 | — | — | EP | disclosed |
| US-20110224304-A1 | BIPHENYLACETAMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-09-15 | — | — | US | disclosed |
| US-20110224304-A1 | BIPHENYLACETAMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142771-A1 | BIPHENYLACETAMIDE DERIVATIVE | HRH3, KCNH3, BRPF3 | PTGER1 1182/4885PTGER4 1681/4885PTGER3 1172/4885 |
| US-20110224304-A1 | BIPHENYLACETAMIDE DERIVATIVE | HRH3, KCNH3, BRPF3 | PTGER1 1182/4885PTGER4 1681/4885PTGER3 1172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.