Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9891082 | 1.00 | TK1 (0.52) | TK1TK2 | |
| SCHEMBL9891085 | 0.86 | LMNA (0.38) | TK1TK2 | |
| SCHEMBL9891088 | 0.86 | TK1 (0.38) | TK1TK2 | |
| SCHEMBL9891089 | 0.86 | TK1 (0.38) | TK1TK2 | |
| SCHEMBL9891090 | 0.86 | TK1 (0.38) | TK1TK2 | |
| SCHEMBL9891086 | 0.86 | LMNA (0.38) | TK1TK2 | |
| SCHEMBL9891087 | 0.86 | TK1 (0.38) | TK1TK2 | |
| SCHEMBL15242196 | 0.79 | TK1 (0.51) | TK1TK2 | |
| SCHEMBL15242194 | 0.79 | TK1 (0.51) | TK1TK2 | |
| SCHEMBL808082 | 0.79 | TK1 (0.51) | TK1TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785629-B2 | Phosphonates synthons for the synthesis of phosphonates derivatives showing better bioavailability | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-07-22 | — | — | US | disclosed |
| US-20130231307-A1 | NOVEL ANTIVIRAL ACYCLIC NUCLEOSIDE PHOSPHONATES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-09-05 | — | — | US | disclosed |
| US-20120142897-A1 | PHOSPHONATES SYNTHONS FOR THE SYNTHESIS OF PHOSPHONATES DERIVATIVES SHOWING BETTER BIOAVAILABILITY | UNIVERSITE D'ORLEANS (FR) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142897-A1 | PHOSPHONATES SYNTHONS FOR THE SYNTHESIS OF PHOSPHONATES DERIVATIVES SHOWING BETTER BIOAVAILABILITY | PNP, PHPT1, TYMP | TK1 75/4885TK2 569/4885 |
| US-20130231307-A1 | NOVEL ANTIVIRAL ACYCLIC NUCLEOSIDE PHOSPHONATES | PNP, TYMP, EIF2AK2 | TK1 91/4885TK2 187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.